Move Often eVery Day (MOV'D): An occupationally-tailored, remotely-delivered, socially-supported short exercise break intervention to decrease sedentary behavior in receptionist office staff

每天经常运动 (MOVD)：一种根据职业量身定制、远程实施、社会支持的短期运动休息干预措施，以减少接待办公室工作人员的久坐行为

• 批准号: 10742427
• 负责人: Marily Oppezzo
• 金额: $ 23.17万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-11 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10742427
• 关键词: Adult; Age; American; Behavior Therapy; Benchmarking; Body Weight; Cardiovascular Diseases; Cartoons; Cause of Death; Clinical; Communication; Consent; Control Groups; Data; Detection; Dropout; Education; Educational process of instructing; Effectiveness; Eligibility Determination; Employee; Ensure; Ethnic Origin; Exercise; Funding; Goals; Grant; Health care facility; Healthcare; Hour; Interruption; Intervention; Interview; Knowledge; Learning; Length; Libraries; Maintenance; Measurement; Modeling; Moderate Exercise; Monitor; Motivation; Movement; National Heart, Lung, and Blood Institute; Noise; Occupational; Occupations; Outcome; Participant; Patient Recruitments; Patients; Personal Satisfaction; Persons; Phase; Physical activity; Population; Positioning Attribute; Privatization; Race; Randomized; Research; Research Personnel; Risk; Risk Factors; Role; Running; Series; Signal Transduction; Social support; Somatotype; Support Groups; Target Populations; Techniques; Testing; Text Messaging; United States National Institutes of Health; Wages; Women' s Group; Work; animation; arm; behavior change; cardiovascular disorder risk; cardiovascular health; cardiovascular risk factor; clinically significant; comparison control; comparison intervention; cost; effective intervention; efficacy testing; efficacy trial; empowerment; evidence base; experimental study; fitbit; fitness; follow-up; high risk population; innovation; moderate-to-vigorous physical activity; novel; peer coaching; peer support; phase III trial; pilot trial; premature; professional atmosphere; programs; recruit; remote delivery; sedentary; sedentary lifestyle; social; social media; study population; tool; treatment group; vigorous intensity

7. Project Summary / Abstract. Prolonged sitting and inadequate moderate to vigorous intensity physical activity (MVPA) are pervasive risk factors for cardiovascular disease (CVD).1–6 CVD is the leading cause of death globally, prematurely taking 655,000 American lives annually.7 Recent research has shown that some benefits of moderate to vigorous physical activity can be accrued in motivationally accessible, short, 2-5 minute bouts throughout the day rather than needing to be a single, longer, continuous bout.8–13 Identifying an effective intervention to interrupt prolonged sitting throughout the day with short, 2-5 minute bouts of MVPA, “exercise snacks,” can provide an accessible way for adults with sedentary jobs to change two CVD risk factors. The current R34 proposes to user-test and pilot the acceptability, feasibility, and clinical signal detection of a novel intervention, MOV’D, to interrupt prolonged sitting with short bouts of MVPA, compared with a Fitbit-only control. Preliminary evidence from an NHLBI K01-funded proof-of-concept study found that evidence-based behavior change technique (BCT) texts to a private, social-media based support group increased steps throughout the day compared to a Fitbit-only control group, but the effects did not last. MOV’D significantly adds to this initial work by: adding videos teaching exercise snacks and BCTs to increase initial and maintained change; adding a peer-coach feature to increase engagement; targeting exercise snacks instead of single exercise bouts; and targeting an at-risk, understudied population (receptionists and clerical health care staff with CVD risk factors). Our team partnered with upper management of Stanford clerical health care staff (low wage positions with high job constraints on physical activity). Together, we have occupationally-tailored the MOV’D program. Before conducting a fully-powered efficacy trial (ORBIT Phase III), we need to user-test and refine two intervention components with our target population (ORBIT Phase Ib; Aim 1); and conduct the necessary acceptability, feasibility, and clinical signal detection pilot trial (ORBIT Phase IIb; Aim 2), which will obtain recruitment and retention parameters to inform the Phase III trial. The Aim 1 user-testing of both the exercise snack and BCT videos will be done with participants from the target population to ensure learning effectiveness, appropriateness, and acceptability. The Aim 2 pilot will randomly assign n=60 participants from the target population to either MOV’D or a Fitbit-only control for 6-weeks, with a 6-month follow-up. We will compare immediate and 6-month data to a priori benchmarks for acceptability, feasibility, and clinical signal detection in workday prolonged sitting bout length and workday MVPA minutes. Results from the proposed R34 will directly inform the R01 for the Phase III trial of MOV’D to test efficacy and duration of effects. The long-term objective is to have a scalable, widely-accessible, remotely-delivered, low-cost behavioral intervention to decrease CVD risk, and is easily adaptable to different populations. Additionally, we will have a library of vetted exercise snack and BCT videos and a guide for occupational-tailoring and adapting videos for researchers in this space.

7.项目概要/摘要。 久坐和中等至剧烈强度的体力活动（MVPA）不足是普遍的风险 心血管疾病（CVD）的主要因素。1 -6 CVD是全球死亡的主要原因，过早服用 655，000美国人每年的生活。7最近的研究表明，适度到剧烈运动的一些好处， 体力活动可以在一天中以动机可及的、短暂的、2-5分钟的回合来积累， 而不是需要一个单一的，更长的，连续的回合。8 -13确定一个有效的干预， 长时间坐在一整天，短暂的2-5分钟的MVPA，“运动零食”，可以提供一个 对于久坐不动的成年人来说，改变两个CVD风险因素的方法是可行的。目前的R34建议 用户测试和试点的可接受性，可行性，和临床信号检测的一种新的干预，MOV 'D， 与仅使用Fitbit的对照组相比，使用短时间的MVPA中断长时间的静坐。初步证据 NHLBI K 01资助的概念验证研究发现，基于证据的行为改变技术 (BCT)发送短信给一个私人的、基于社交媒体的支持小组， 仅使用Fitbit的对照组，但效果并不持久。MOV的D显着增加了这一初步的工作：添加 视频教学运动小吃和BCT，以增加初始和维持的变化;增加同伴教练 功能，以增加参与;针对运动零食，而不是单一的运动回合;并针对 高危、未充分研究的人群（具有心血管疾病风险因素的接待员和文书卫生保健人员）。我们的团队 与斯坦福大学的高级管理人员合作（低工资职位，高工作 身体活动的限制）。我们一起为职业量身定制了MOV 'D计划。之前 进行一项全面的疗效试验（ORBIT III期），我们需要用户测试和完善两种干预措施， 组件与我们的目标人群（ORBIT阶段Ib;目标1）;并进行必要的可接受性， 可行性和临床信号检测试点试验（ORBIT IIb期;目标2），将招募和 保留参数，以告知III期试验。Aim 1运动零食和BCT的用户测试 将为目标人群的参与者制作视频，以确保学习效果， 适当性和可接受性。目标2试点将从目标中随机分配n=60名参与者 将受试者群体置于MOV 'D或仅Fitbit对照组中6周，并进行6个月随访。我们将比较 即时和6个月的数据，以先验基准的可接受性，可行性和临床信号检测， 工作日久坐时间和工作日MVPA分钟数。建议的R34的结果将直接 通知R 01进行MOV 'D的III期试验，以测试疗效和作用持续时间。长期目标 是有一个可扩展的，广泛访问的，远程交付的，低成本的行为干预，以减少心血管疾病 风险，并易于适应不同的人群。此外，我们将有一个图书馆， 小吃和BCT视频和职业定制指南，并为研究人员在这个领域的适应视频。