Market Assessment Study of Leech-mimic 3D Printed Origami Sensor to Monitor Electrophysiological Signals

西蒙·弗雷泽大学技术许可办公室正在进行Adventus的一项市场评估研究，该研究由NSERC创意到创新资助计划支持，针对SFU机电系统工程学院教授Woo Soo Kim博士开发的一项技术，名为“Leech-Mimic 3D打印折纸(LMO)传感器，由具有伸展小体的非膨胀性尖端组成，用于监测电生理信号”。血压监测在医学诊断中起着至关重要的作用，因为高血压与多种慢性病密切相关。心血管疾病的日益流行和日益老龄化的人口导致对个人医疗系统的需求不断上升，这些系统在患者的日常生活中收集患者的血压。因此，无需临床设置(例如用于远程或一般医疗保健监测的移动或可穿戴设备)的准确和/或频繁的血压监测有望推动全球心电传感器市场。事实上，对于便携式设备，心电和PPG(光体积描记)技术都变得容易获得、低成本和方便。脉冲到达时间(PAT)参数表示脉冲波形从心脏到远端位置所花费的时间，通常用于配对的心电-PPG传感系统连续监测血压。使用PAT进行血压监测时，心脏附近需要可靠的心电信号，远端需要PPG信号。因此，干燥的心电电极在皮肤上的稳定定位对于获得有效的心电信号是至关重要的。SFU的研究人员已经开发出一种模仿水蚤的3D打印折纸(LMO)传感器，该传感器由带有伸展小体的非伸展尖端组成，用于监测电生理信号。仿水蚤结构(LMO)提供稳定的接触，并对人体皮肤施加可靠但轻微的吸力，使LMO在患者运动时仍附着在人体皮肤上。与目前用于心电和血压监测的湿凝胶型电极相比，这种用于心血管监测系统的干式电极使监测时间更快、更舒适。

The Simon Fraser University Technology Licensing Office has Adventus work on a market assessment study supported through the NSERC Idea to Innovation grant program, for a technology entitled "Leech-mimic 3D printed origami (LMO) sensor composed of the non-auxetic tip with auxetic bodies to monitor electrophysiological signals" developed by Dr. Woo Soo Kim, Professor in the School of Mechatronic Systems Engineering at SFU. Monitoring of blood pressure (BP) plays a crucial role in medical diagnosis because high BP is deeply related to several chronic diseases. The increasing prevalence of cardiovascular diseases and the growing aging population are leading to rising demand for personal healthcare systems that collect the BP of patients during their daily life. Therefore, accurate and/or frequent BP monitoring without clinical settings (such as mobile or wearable devices for remote or general healthcare monitoring) is anticipated to drive the global ECG sensor market. In fact, both ECG and PPG (photoplethysmography) technologies are becoming easily available, low-cost, and convenient with portable devices. The pulse arrival time (PAT) parameter, indicating the time taken from the pulse waveforms to traverse from the heart to a distal site, is often used with the paired ECG-PPG sensing system monitoring the BP continuously. The BP monitoring with PAT requires reliable ECG signals near the heart and PPG signals on the distal site. Thus, stable positioning of dry ECG electrodes on the skin is essential to obtain effective ECG signals. SFU researchers have developed a leech-mimic 3D printed origami (LMO) sensor composed of the non-auxetic tip with auxetic bodies to monitor electrophysiological signals. The leech-mimic structure (LMO) provides stable contacts and applies reliable but slight suction to the human skin so that the LMO is still attached to the human skin when the patient is in motion. This dry electrode for cardiovascular monitoring systems makes monitoring time faster and much more comfortable compared to the current wet gel-type electrodes used in monitoring ECG and BP.