Design of high performance antiviral and antibacterial cold spray coatings for continuous disinfection on high-touch surfaces

目前用于控制SARS-CoV-2通过表面（即“污染物”）传播的预防措施强调了表面消毒的重要性。为了限制污染物的传播，大多数商业建筑、学校和其他公共基础设施都改进了清洁和消毒方案，并增加了使用频率，这给其运营增加了财政和后勤负担。因此，对可靠和经济的解决方案的需求很高，该解决方案可以在经常接触的表面上提供被动和持续的消毒。该项目旨在继续我们在CRSNG-COVID-19资助项目中启动的工作，为经常接触的表面设计高性能抗病毒涂层。该研究将侧重于(1)开发铜基材料特性对病毒和细菌失活机制的影响的知识，以开发对多种病毒和细菌具有增强活性的涂层；(2)开发能够在正常使用条件下（包括使用苛刻化学品的清洁和消毒方案）保持多年抗病毒和抗菌性能的涂层。该项目的合作伙伴包括麦吉尔大学，提供材料和病毒与细菌的专业知识，INRS提供表面相互作用和NRC的知识，与麦吉尔和INRS合作开发材料和加工，并帮助三家合作公司将研究成果产业化和商业化。在项目期间，粉末公司5N Plus将根据所获得的结果开发一种具有该应用市场最佳成分和性能的金属粉末；Polycontrols将为该应用制造涂料技术的工业演示，生产涂料和商业化涂层系统；Hatch有限公司将通过性能数据和可持续性分析来响应市场需求，使其能够用这种涂料升级公共基础设施。

The preventive measures currently applied to contain the transmission of SARS-CoV-2 by surfaces (i.e.'fomites') have highlighted the importance of surface disinfection. In order to limit transmission by fomites,most commercial buildings, schools and other public infrastructure have improved their cleaning and disinfection protocols and increased their frequencies, adding financial and logistical burdens to their operation. Therefore, there is a high demand for a reliable and economical solution that would provide passive and continuous disinfection on frequently touched surfaces. This project aims to continue our efforts, initiated in a project funded by a CRSNG-COVID-19 grant, in the design of high performance antiviral coatings for frequently touched surfaces. The research will focus on (1) the development of knowledge on the influence of properties of copper-based materials on the mechanisms of inactivation of viruses and bacteria to develop coatings with enhanced activities against a wide range of viruses and bacteria and (2) develop coatings that maintain their antiviral and antibacterial performance for years by withstanding normal conditions of use, including cleaning and disinfection protocols that use harsh chemicals. The project partners include McGill University, supplying Materials and Virus and Bacteria expertise, INRS bringing knowledge of surface interactions and NRC, working with McGill and INRS on materials and processing developments and helping the three collaborating companies industrialize and commercialize the findings. During the project, the powder company, 5N Plus will develop, based on the results obtained, a metallic powder having the composition and the properties optimal for the marketing of this application; Polycontrols will manufacture industrial demonstrations of the coating technology, produce coatings and commercialize coating systems for this application; Hatch Ltd. will respond to market demands with performance data and sustainability analysis, allowing it to upgrade public infrastructures with such coatings.