Photonics of Surfaces and Interfaces

我的研究项目集中在使用波导和等离子体的新型表面和界面的研究和设计上，这些表面和界面直接位于相邻物体的表面或界面上，呈现出一种薄膜光（称为倏逝场）。在纳米等离子体动力学中，金属纳米粒子（NPs）显示出非常强的光膜和强吸收带，允许用于高灵敏度化学传感器的比色或透射装置。光膜也应用于表面显微镜。散射/荧光消失显微镜用于研究表面和界面，涂层，细菌膜形成和单细胞-基质相互作用。我的团队以其高度复杂的跨学科研究和成就而闻名于世，其中包括许多具有高影响力的出版物，杰出的会议贡献和训练有素的学生以及他们自己的成功故事。我的研究将围绕基础表面/界面科学的三个关键主题展开。目标和方法用于（生物）传感平台的aunp：将开发两种新的多路复用形式的精益和简易传感器方案，该方案集成了我们新开发的用于通道波导定义的aunp条带加载技术以及我们最近发现和描述的局域表面等离子体共振的线宽缩小效应。将通过制定一种回收方法（使用后安全处置）来解决非硝化生物传感器平台的健康和环境问题。2.（生物）-界面，涂层和胶原膜：涉及在植入物上制造高度定向的胶原膜，以增强生物相容性，避免宿主排斥，并模仿各向异性组织的物理特性。一种新颖的Langmuir-Blodgett （LB）槽设计与圆形封闭屏障将建立。此外，还将开发一种制备独立定向胶原蛋白薄膜的技术。有了这些独立的膜，可能是多层的，新的角膜植入策略应该是可行的。3. 波导倏逝场显微镜：一种动态操作的倏逝显微镜和由聚合物（刚性和柔性）制成的新型高光学质量波导芯片将被开发出来，以研究和提高细胞对技术表面的粘附质量（对医疗植入物很重要）。同时展望了研制小型化婴儿起搏器的科学基础。除了HQP在最先进的技术和研发战略的多学科背景下的优秀培训，可能转化为加拿大工业，并在同行评审的高影响力期刊上发表文章外，该研究计划将加强和促进加拿大现在和未来的高科技研发，因此将为加拿大的经济财富和加拿大人的生活做出积极贡献。

INTRODUCTION My research program is focused on the study and design of novel surfaces and interfaces using waveguides and plasmonics, which exhibit a thin film of light (called evanescent field) directly located at a surface or an interface to an adjacent object. In nano-plasmonics, metal nanoparticles (NPs) show a very strong film of light and a strong absorption band, allowing colorimetric or transmission devices for high sensitivity chemical sensors. The light films are also applied in surface microscopy. Scattering/fluorescence evanescent microscopy is used to study surfaces and interfaces, coatings, bacteria film formation and single cell-substratum interaction. My group is known world-wide for its highly sophisticated, interdisciplinary research and achievements through many scientific contributions in form of high impact publications, outstanding conference contributions and well-trained students with their own success stories. My research will center around three key themes critical for fundamental surface/interface science. OBJECTIVES AND APPROACHES 1.AuNPs for (Bio)-Sensing Platforms: two new lean and facile sensor schemes in multiplexing form integrating our newly developed AuNP-strip-loading technology for channel waveguide definition as well as the recently discovered and described (by us) line-width narrowing effect of the localized surface plasmon resonance will be developed. Health and environmental issues of AuNPs will be addressed by developing a recycling method for the AuNP sensor platforms (safe disposal after use). 2.(Bio)-Interfaces, Coatings and Collagen Films: involves the fabrication of highly oriented collagen films on implants for an enhanced biocompatibility, avoiding the host rejection, and the mimicking of anisotropic tissue with its physical characteristics. A novel Langmuir-Blodgett (LB) trough design with a circularly closing barrier will be established. In addition, a technology to fabricate free-standing oriented collagen films will be developed. With these free-standing films, possibly multilayered, new cornea implant strategies should be enabled. 3. Waveguide Evanescent Field Microscopy: a dynamically operating evanescent microscope and novel high optical quality waveguide chips fabricated from polymers (stiff and flexible) will be developed to allow studying and enhancing the adhesion-quality of cells to technical surfaces (important for medical implants). Also envisioned is the scientific groundwork for developing a miniaturized infant pace maker. SIGNIFICANCE AND IMPACT Besides the excellent training of HQP in a multidisciplinary setting on state-of-the-art technology and R&D strategies, possible translation to Canadian industry, and the publications in peer-reviewed, high impact journals, this research program will enhance and foster Canada's high tech R&D now and in the future, and will therefore be contributing actively to Canada's economic wealth and to Canadian life.