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Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer

Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer
通过噬菌体和细菌 S 层的基因工程揭开艰难梭菌中病毒与宿主相互作用的神秘面纱
批准号:
494839
负责人:
Fortier Louis-Charles
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-09-01 至 2024-09-01

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中文摘要
翻译
使用被称为噬菌体(或简称噬菌体)的裂解病毒来杀死多重耐药细菌,如人类病原体艰难梭状芽胞杆菌(CD),最近引起了人们的极大兴趣。利用基因工程操控微生物群
英文摘要
The use of lytic viruses called bacteriophages (or simply phages) to kill multidrug resistant bacteria such as the human pathogen Clostridioides difficile (Cd) has gained a lot of interest recently. The manipulation of the microbiome with genetically-engi
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