Bacteriophages in the ageing gut as targeted therapeutics

老化肠道中的噬菌体作为靶向治疗

• 批准号: 2893971
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2893971
• 关键词: Bacteriophages; ageing; gut; targeted; therapeutics

Bacteriophages are the most abundant biological entity on the planet, but their role in the human microbiome is poorly understood. In this project, the student will use a combination of viromics and culturing to investigate the bacteriophages in the gut of an elderly patient cohort. The student will use our state-of-the-art model systems mimicking the human gut to develop interventional strategies to treat dysbiosis.

噬菌体是地球上最丰富的生物实体，但它们在人类微生物组中的作用却知之甚少。在这个项目中，学生将使用病毒组学和培养的组合来研究老年患者队列肠道中的噬菌体。学生将使用我们最先进的模拟人类肠道的模型系统来开发治疗生态失调的干预策略。