The Novel Relationship between Urban Air Pollution and Epilepsy: A Time Series Study.
The Novel Relationship between Urban Air Pollution and Epilepsy: A Time Series Study.
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城市空气污染与癫痫之间的新关系：时间序列研究
DOI：
10.1371/journal.pone.0161992
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Cai TJ
中科院分区：
文献类型：
--
作者：
Xu C;Fan YN;Kan HD;Chen RJ;Liu JH;Li YF;Zhang Y;Ji AL;Cai TJ
关于环境污染和癫痫发作之间的关系的数据是有限的。本研究的目的是探讨急性空气污染暴露与癫痫发作之间的关系。在中国污染严重的大都会西安进行了一项基于医院记录的研究。获得每日基线数据。时间序列泊松回归模型被用来分析空气污染和癫痫之间的关联。NO2、SO2和O3浓度每增加10 μg/m3，对应的排放量为3.17%。（95%CI：1.41%，4.93%），3.55%（95%Cl：1.93%，5.18%）和-0.84%（95%CI：-1. 58%，0. 09%）增加了同期门诊癫痫患者的就诊次数，性别和年龄对癫痫患者的就诊次数有显著影响。NO2和SO2的影响在调整PM2.5后会更强。对于O3，经NO2调整后，下降了-1.14%（95%Cl：-1.90%，-0.39%）。滞后模型表明，最显着的影响，同时天证明。我们发现了以前未记录的短期空气污染暴露与癫痫之间的关系：虽然NO2和SO2与癫痫的门诊就诊呈正相关，但O3可能与风险降低有关。
The data concerning the association between environmental pollution and epilepsy attacks are limited. The aim of this study was to explore the association between acute air pollution exposure and epilepsy attack. A hospital record-based study was carried out in Xi’an, a heavily-polluted metropolis in China. Daily baseline data were obtained. Time-series Poisson regression models were applied to analyze the association between air pollution and epilepsy. A 10 μg/m3 increase of NO2, SO2, and O3 concentrations corresponded to 3.17% (95%Cl: 1.41%, 4.93%), 3.55% (95%Cl: 1.93%, 5.18%), and -0.84% (95%Cl: -1.58%, 0.09%) increase in outpatient-visits for epilepsy on the concurrent days, which were significantly influenced by sex and age. The effects of NO2 and SO2 would be stronger when adjusted for PM2.5. As for O3, a -1.14% (95%Cl: -1.90%, -0.39%) decrease was evidenced when adjusted for NO2. The lag models showed that the most significant effects were evidenced on concurrent days. We discovered previously undocumented relationships between short-term air pollution exposure and epilepsy: while NO2 and SO2 were positively associated with outpatient-visits of epilepsy, O3 might be associated with reduced risk.
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影响因子：
9.3
作者：
Ajamieh, H;Merino, N;Leon, OS
通讯作者：
Leon, OS
影响因子：
11.8
作者：
Cakmak, Sabit;Dales, Robert E.;Blanco Vidal, Claudia
通讯作者：
Blanco Vidal, Claudia
影响因子：
6.3
作者：
Freire, Carmen;Ramos, Rosa;Olea, Nicolas
通讯作者：
Olea, Nicolas
DOI：
10.1080/03601239209372767
发表时间：
1992-01-01
影响因子：
2
作者：
FARAHANI, H;HASAN, M
通讯作者：
HASAN, M
影响因子：
3.6
作者：
Berg, Anne T.
通讯作者：
Berg, Anne T.