Blueberry and mulberry juice prevent obesity development in C57BL/6 mice.
Blueberry and mulberry juice prevent obesity development in C57BL/6 mice.
复制标题
蓝莓和桑葚汁预防 C57BL/6 小鼠肥胖
DOI：
10.1371/journal.pone.0077585
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Chen W
中科院分区：
文献类型：
--
作者：
Wu T;Tang Q;Gao Z;Yu Z;Song H;Zheng X;Chen W
Objectives To establish whether blueberry (Vaccinium ashei) and mulberry (Morus australis Poir) juice, anthocyanin rich fruit juice, may help counteract obesity. Design And Methods: Four-week-old C57BL/6 mice were fed a high-fat diet (HFD) with or without blueberry and mulberry juice for 12 weeks. Body weight, serum and hepatic lipids, liver and adipose tissues morphology, insulin and leptin were assessed. Results Mice fed HFD exhibited increased body weight, insulin resistance, serum and hepatic lipids. In comparison, blueberry and mulberry juice inhibited body weight gain, decreased the serum cholesterol, reduced the resistance to insulin, attenuated lipid accumulation and decreased the leptin secretin. Conclusion These results indicate that blueberry and mulberry juice may help counteract obesity.
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