Has GWAS lost its status as a paragon of open science?

Has GWAS lost its status as a paragon of open science?
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DOI:
10.1371/journal.pbio.3001242
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发表时间:
2021-05
期刊:
影响因子:
9.8
通讯作者:
Munafò M
Munafò M
中科院分区:
生物学1区
文献类型:
--
作者:
Burt C;Munafò M

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基因组研究在开放科学中处于领先地位,通过共享材料、结果和数据,全基因组关联研究(GWAS)延续了这一传统。协调的质量控制程序也有助于得出可靠的结论。然而,近几年来,全球气候变化网络的透明度有所下降。在这里,我们评估一些远离开放科学实践的转变,目的是鼓励对这些问题的讨论。基因组研究通过共享材料、结果和数据,在开放科学中走在了前列--这一传统被全基因组关联研究所延续。协调的质量控制程序也有助于得出可靠的结论。但这篇《透视》的文章想知道,这些标准现在是否正在倒退。
Genomic research led the way in open science, a tradition continued by genome-wide association studies (GWAS)—through the sharing of materials, results, and data. Coordinated quality control procedures also contributed to robust findings. However, recent years have seen declines in GWAS transparency. Here, we assess some shifts away from open science practices with the aim of stimulating a discussion of these issues. Genomic research led the way in open science – a tradition continued by genome-wide association studies – through the sharing of materials, results and data. Coordinated quality control procedures also contributed to robust findings. But this Perspective article wonders whether these standards are now slipping back.
基因发现和多基因预测,从基因组全基因组协会的教育程度研究中,有110万个人。
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