Racial and Ethnic Cardiometabolic Risk Disparities in the Type 1 Diabetes Exchange Clinic Registry Cohort.
Racial and Ethnic Cardiometabolic Risk Disparities in the Type 1 Diabetes Exchange Clinic Registry Cohort.
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1 型糖尿病交换诊所登记队列中的种族和民族心脏代谢风险差异。
DOI：
10.1016/j.eprac.2022.10.003
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发表时间：
2022-12
影响因子：
4.2
通讯作者：
Hatipoglu, Betul
中科院分区：
文献类型：
--
作者：
Griggs, Stephanie;Blanchette, Julia E.;Hickman Jr, Ronald L.;Magny-Normilus, Cherlie;Baskin, Revital Gorodeski;Margevicius, Seunghee;Hatipoglu, Betul
关键词：
确定考虑到社会经济贫困，来自历史上代表性不足的种族群体的个体是否比历史上代表性的1型糖尿病（T1 D）个体具有更高的心脏代谢风险。我们使用多变量logistic和线性回归模型，分别在6，320个邮政编码列表区域中，通过种族/种族相互作用检查每个心脏代谢风险因素和心脏代谢风险负担评分的社会经济剥夺（上10百分位数）。我们还分别测定了非西班牙裔白色（n = 15，746）、非西班牙裔黑人（n = 1，019）、西班牙裔（n = 1，115）和其他（n = 887）的低、中、高心脏代谢风险（定义为高血压、肥胖、血脂异常和脱靶肥胖的0、1-2和3个或更多风险因素）的年龄校正患病率。样本包括18，767名患有T1 D的青少年和成人。与非西班牙裔白色个体相比，非西班牙裔黑人更可能具有高心脏代谢风险特征，包括脱靶风险增加4.5倍，收缩期高血压增加2倍，以及较高心脏代谢风险负担增加0.29（未校正）和0.46（校正）（p <0.01）。与非西班牙裔白色人相比，西班牙裔的脱靶率增加了3.4倍，但超重/肥胖或收缩期高血压的可能性较小。然而，考虑协变量后，超重/肥胖和高血压的可能性较低并不持续。有必要调查种族/民族代表性不足的心脏代谢健康的其他决定因素，包括结构性种族主义和T1 D患者心脏代谢护理中的隐性偏见。
To determine whether individuals from a historically underrepresented racial group have higher cardiometabolic risk than historically represented individuals with type 1 diabetes (T1D) considering socioeconomic deprivation. We used multivariable logistic and linear regression models to examine socioeconomic deprivation (upper 10th percentile) by race/ethnicity interaction for each cardiometabolic risk factor and cardiometabolic risk burden score, respectively, across 6,320 zip code tabulation areas. We also determined age-adjusted prevalence of low, moderate, and high cardiometabolic risk defined as 0, 1–2, and 3 or more risk factors of hypertension, obesity, dyslipidemia, and off-target glycemia for Non-Hispanic White (n = 15,746), Non-Hispanic Black (n = 1,019), Hispanic (n = 1,115), and Other (n = 887) respectively. The sample comprised 18,767 adolescents and adults with T1D. Those identifying as Non-Hispanic Black were more likely to have a high cardiometabolic risk profile, including a 4.5-fold increase in the odds of off-target glycemia, a 2-fold increase in the odds of systolic hypertension, and a 0.29 (unadjusted) and 0.46 (adjusted) increase in a higher cardiometabolic risk burden compared to Non-Hispanic White individuals (p < .01). Those identifying as Hispanic had a 3.4-fold increase in the odds of off-target glycemia but were less likely to be overweight/obese or have systolic hypertension compared to Non-Hispanic White. However, the lower likelihood of overweight/obesity and hypertension did not persist after considering covariates. There is a need to investigate additional determinants of racially/ethnically underrepresented cardiometabolic health, including structural racism and implicit bias in cardiometabolic care for individuals with T1D.
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影响因子：
37.8
作者：
Churchwell, Keith;Elkind, Mitchell S. V.;Williams, Olajide
通讯作者：
Williams, Olajide
影响因子：
8.3
作者：
Aggarwal, Rahul;Chiu, Nicholas;Kazi, Dhruv S.
通讯作者：
Kazi, Dhruv S.
DOI：
10.1126/science.1224648
发表时间：
2012-09-21
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Ludwig J;Duncan GJ;Gennetian LA;Katz LF;Kessler RC;Kling JR;Sanbonmatsu L
通讯作者：
Sanbonmatsu L
影响因子：
3.4
作者：
Butler, Danielle C.;Petterson, Stephen;Bazemore, Andrew W.
通讯作者：
Bazemore, Andrew W.
影响因子：
5.4
作者：
Agarwal, Shivani;Schechter, Clyde;Long, Judith A.
通讯作者：
Long, Judith A.