Differences in gamma frequencies across visual cortex restrict their possible use in computation.

Differences in gamma frequencies across visual cortex restrict their possible use in computation.
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DOI:
10.1016/j.neuron.2010.08.004
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发表时间:
2010-09-09
期刊:
影响因子:
16.2
通讯作者:
Maunsell, John H. R.
Maunsell, John H. R.
中科院分区:
医学1区
文献类型:
--
作者:
Ray, Supratim;Maunsell, John H. R.

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伽马波段(30-80 Hz)的神经元振荡被认为在特征绑定或建立神经通信通道中发挥核心作用。对于这些功能,伽马节律频率必须在编码刺激特征的神经组件之间保持一致。在这里,我们测试的依赖性γ频率的刺激对比度在清醒的行为猕猴的V1皮层,并表明,γ频率单调增加与对比度。刺激对比度随时间的变化导致快速时标上的可靠伽马频率调制。此外,在间隔仅为400 μm的同时记录的神经元集合体中,其对比度在空间上变化的大刺激以显著不同的频率产生伽马节律,使得伽马节律成为结合或通信的不良候选者,至少在V1中是如此。相反,我们的研究结果表明,伽马节律产生于兴奋和抑制之间的局部相互作用。
Neuronal oscillations in the gamma band (30-80 Hz) have been suggested to play a central role in feature binding or establishing channels for neural communication. For these functions, the gamma rhythm frequency must be consistent across neural assemblies encoding the features of a stimulus. Here we test the dependence of gamma frequency on stimulus contrast in V1 cortex of awake behaving macaques and show that gamma frequency increases monotonically with contrast. Changes in stimulus contrast over time leads to a reliable gamma frequency modulation on a fast timescale. Further, large stimuli whose contrast varies across space generate gamma rhythms at significantly different frequencies in simultaneously recorded neuronal assemblies separated by as little as 400 μm, making the gamma rhythm a poor candidate for binding or communication, at least in V1. Instead, our results suggest that the gamma rhythm arises from local interactions between excitation and inhibition.
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