Diffusion-weighted imaging in head and neck cancers.
Diffusion-weighted imaging in head and neck cancers.
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在头部和颈部癌症中进行扩散加权成像。
DOI：
10.2217/fon.09.77
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发表时间：
2009-09
期刊：
影响因子：
--
通讯作者：
Poptani H
中科院分区：
文献类型：
--
作者：
Chawla S;Kim S;Wang S;Poptani H
本文综述了弥散加权成像（DWI）在头颈部肿瘤的诊断、预后和治疗反应监测中的应用。DWI测定的表观扩散系数（ADC）值有助于肿瘤分期和亚厘米淋巴结转移的检测。ADC值还能区分癌与淋巴瘤、良性病变与恶性肿瘤、肿瘤坏死与脓肿。低预处理ADC值通常预示着对放化疗的有利反应。这些有希望的报告表明，DWI有可能作为头颈癌诊断和监测治疗反应的潜在生物标志物。鉴于不同唾液腺肿瘤ADC值重叠，在解释这些结果时应谨慎，并应考虑其他影像学参数以更好地诊断。敏感性和运动诱发的伪影有时会降低DWI图像质量；然而，正在开发新的技术来克服这些缺点。
This article reviews the utility of diffusion-weighted imaging (DWI) in the diagnosis, prognosis and monitoring of treatment response in tumors arising in the head and neck region. The apparent diffusion coefficient (ADC) value, determined from DWI, can help in cancer staging and detection of subcentimeter nodal metastasis. The ADC value also discriminates carcinomas from lymphomas, benign lesions from malignant tumors and tumor necrosis from abscesses. Low pretreatment ADC values typically predict a favorable response to chemoradiation therapy. These promising reports indicate the potential of DWI as a potential biomarker for diagnosis and monitoring of treatment response in head and neck cancers. In view of the overlapping ADC values between different salivary gland tumors, care should be taken when interpreting these results and other imaging parameters should be considered for a better diagnosis. Susceptibility and motion-induced artifacts may sometimes degrade DWI image quality; however, novel techniques are being developed to overcome these drawbacks.
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影响因子：
19.7
作者：
FRELING, NJM;MOLENAAR, WM;THIJN, CJP
通讯作者：
THIJN, CJP
DOI：
10.1002/hed.10004
发表时间：
2002-02-01
影响因子：
2.9
作者：
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通讯作者：
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影响因子：
19.7
作者：
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影响因子：
158.5
作者：
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通讯作者：
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影响因子：
168.9
作者：
Dzik-Jurasz, A;Domenig, C;Doran, S
通讯作者：
Doran, S