Interoception in anxiety and depression.

Interoception in anxiety and depression.
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DOI:
10.1007/s00429-010-0258-9
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发表时间:
2010-06
影响因子:
3.1
通讯作者:
Stein, Murray B.
Stein, Murray B.
中科院分区:
医学3区
文献类型:
--
作者:
Paulus, Martin P.;Stein, Murray B.

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我们回顾了与抑郁和焦虑相关的内感受文献,重点是信念和异感。增加但嘈杂的传入内感受输入,自我参照和基于信念的状态,以及自上而下的调制预测性差的信号之间的联系被整合到抑郁症和焦虑症的神经解剖学和处理模型。这种概念化的优点是能够具体地检查基本的内感受,自我指涉的信念为基础的状态,并增强自上而下的调制,以减弱可预测性差之间的接口。我们的结论是,抑郁症和焦虑症不是简单的内感受性障碍,但改变内感受性状态的结果,嘈杂放大的自我参照内感受性预测信念状态。
We review the literature on interoception as it relates to depression and anxiety, with a focus on belief, and alliesthesia. The connection between increased but noisy afferent interoceptive input, self-referential and belief-based states, and top-down modulation of poorly predictive signals is integrated into a neuroanatomical and processing model for depression and anxiety. The advantage of this conceptualization is the ability to specifically examine the interface between basic interoception, self-referential belief-based states, and enhanced top-down modulation to attenuate poor predictability. We conclude that depression and anxiety are not simply interoceptive disorders but are altered interoceptive states as a consequence of noisily amplified self-referential interoceptive predictive belief states.
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发表时间: 1999-06-01
期刊: NEUROIMAGE
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