Evolutionarily conserved odorant receptor function questions ecological context of octenol role in mosquitoes.

Evolutionarily conserved odorant receptor function questions ecological context of octenol role in mosquitoes.
复制标题

进化保守的气味受体功能质疑八烯醇在蚊子中作用的生态环境。

DOI:
10.1038/srep37330
复制
发表时间:
2016-11-16
期刊:
影响因子:
4.6
通讯作者:
Bohbot JD
Bohbot JD
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Dekel A;Pitts RJ;Yakir E;Bohbot JD

文献摘要

参考文献

被引文献

相似文献

嗅觉是昆虫适应广泛生境的关键。在过去的三十年里,通过吸血昆虫检测辛烯醇主要是在动物宿主寻找的背景下理解的。最近在严格以花蜜为食的象蚊Toxorhynchites amboinensis(TaOr 8)中发现了一个保守的辛烯醇受体基因,这表明了一种不同的生物学作用。在这里,我们表明,TaOR 8是一个功能性的直系同源物,其对应物在吸血蚊子显示选择性对(R)-对映体的辛烯醇和敏感性的驱虫剂避蚊胺。这些发现表明,虽然OR 8的功能在蚊子的进化过程中一直保持不变,但这种受体的运作环境在血液和花蜜喂养的蚊子中有所不同。
Olfaction is a key insect adaptation to a wide range of habitats. In the last thirty years, the detection of octenol by blood-feeding insects has been primarily understood in the context of animal host-seeking. The recent discovery of a conserved octenol receptor gene in the strictly nectar-feeding elephant mosquito Toxorhynchites amboinensis (TaOr8) suggests a different biological role. Here, we show that TaOR8 is a functional ortholog of its counterparts in blood-feeding mosquitoes displaying selectivity towards the (R)-enantiomer of octenol and susceptibility to the insect repellent DEET. These findings suggest that while the function of OR8 has been maintained throughout mosquito evolution, the context in which this receptor is operating has diverged in blood and nectar-feeding mosquitoes.
DOI: 10.1007/s10886-014-0403-7
发表时间: 2014-03-01
影响因子: 2.3
作者:
Jayanthi, Pagadala D. Kamala;Kempraj, Vivek;Bruce, Toby J. A.
通讯作者: Bruce, Toby J. A.
DOI: 10.1111/j.1365-2583.2007.00748.x
发表时间: 2007-10-01
影响因子: 2.6
作者:
Bohbot, J.;Pitts, R. J.;Zwiebel, L. J.
通讯作者: Zwiebel, L. J.
DOI: 10.1007/s00114-015-1297-0
发表时间: 2015-10-01
期刊: SCIENCE OF NATURE
影响因子: 1.8
作者:
Bendera, M.;Ekesi, S.;Torto, B.
通讯作者: Torto, B.
DOI: 10.1046/j.1365-3032.1998.233091.x
发表时间: 1998-09-01
影响因子: 1.5
作者:
Collins, LE;Blackwell, A
通讯作者: Blackwell, A
DOI: 10.1371/journal.pone.0012138
发表时间: 2010-08-11
期刊: PloS one
影响因子: 3.7
作者:
Bohbot JD;Dickens JC
通讯作者: Dickens JC