CRISPR technology is revolutionizing the improvement of tomato and other fruit crops
CRISPR technology is revolutionizing the improvement of tomato and other fruit crops
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CRISPR 技术正在彻底改变番茄和其他水果作物的改良
DOI：
10.1038/s41438-019-0159-x
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发表时间：
2019-06
影响因子：
8.7
通讯作者：
Zhu Hongliang
中科院分区：
文献类型：
--
作者：
Wang Tian;Zhang Hongyan;Zhu Hongliang
水果是必需营养素的主要来源，并在世界某些地区作为主食。随着世界范围内人口的增加和气候的变化，迫切需要生产高产和增强环境适应性的水果作物，而传统育种不太可能满足这种需求。幸运的是，成簇规则间隔短回文重复序列 (CRISPR) 技术为水果作物改良的新领域铺平了道路，从而彻底改变了植物育种。本文重点介绍了 CRISPR 系统的机制和优化及其在果树作物中的应用，包括生物和非生物胁迫抗性、果实品质改良和驯化。还讨论了争议和未来前景。
Fruits are major sources of essential nutrients and serve as staple foods in some areas of the world. The increasing human population and changes in climate experienced worldwide make it urgent to the production of fruit crops with high yield and enhanced adaptation to the environment, for which conventional breeding is unlikely to meet the demand. Fortunately, clustered regularly interspaced short palindromic repeat (CRISPR) technology paves the way toward a new horizon for fruit crop improvement and consequently revolutionizes plant breeding. In this review, the mechanism and optimization of the CRISPR system and its application to fruit crops, including resistance to biotic and abiotic stresses, fruit quality improvement, and domestication are highlighted. Controversies and future perspectives are discussed as well.
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