Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography.

Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography.
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DOI:
10.1364/oe.16.016410
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发表时间:
2008-10-13
期刊:
影响因子:
3.8
通讯作者:
Hitzenberger CK
Hitzenberger CK
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Götzinger E;Pircher M;Geitzenauer W;Ahlers C;Baumann B;Michels S;Schmidt-Erfurth U;Hitzenberger CK

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我们提出了一种新的方法来识别和分割人类视网膜偏振敏感光学相干断层扫描(PS-OCT)图像中的视网膜色素上皮(RPE)。相反,以前的,基于强度的分割算法,我们的方法使用的RPE的内在组织属性:其去偏振,或偏振扰效应的后向散射光。提出并讨论了两种不同的分割算法:一种基于延迟数据的简单算法,以及一种基于平均斯托克斯矢量元素计算的偏振态局部变化的更复杂算法。通过使用最先进的谱域PS-OCT仪器,我们证明了健康和患病的眼睛的方法。
We present a new method for identifying and segmenting the retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous, intensity based segmentation algorithms, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. Two different segmentation algorithms are presented and discussed: a simpler algorithm based on retardation data, and a more sophisticated algorithm based on local variations of the polarization state calculated from averaged Stokes vector elements. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes.
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