Odorant receptor from the southern house mosquito narrowly tuned to the oviposition attractant skatole.
Odorant receptor from the southern house mosquito narrowly tuned to the oviposition attractant skatole.
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DOI：
10.1007/s10886-010-9828-9
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发表时间：
2010-08
影响因子：
2.3
通讯作者：
Leal, Walter S.
中科院分区：
文献类型：
--
作者：
Hughes, David T.;Pelletier, Julien;Luetje, Charles W.;Leal, Walter S.
关键词：
产卵引诱剂是环境线索，使库蚊妊娠雌蚊找到合适的地点产卵，因此，可以利用环境友好的策略，控制蚊子种群。天然存在的粪臭素已被鉴定为南方家蚊致倦库蚊的产卵引诱剂。之前，我们在Cx中识别出。致倦鸟雌性触角的嗅觉受体神经元（ORN）对粪臭素高度敏感，气味结合蛋白参与检测这种化学信息素。在这里，我们描述的气味受体（OR），CquiOR 10，这是狭隘的调整粪臭素时，在非洲爪蟾卵母细胞系统中表达的表征。异源表达的CquiOR 10产生的气味诱导的反应曲线表明，该OR在对粪臭素敏感的蚊子ORN中表达。然而，牛儿基丙酮，刺激触角ORN，没有检测到CquiOR 10-表达卵母细胞，从而提出了有趣的问题产卵引诱剂在蚊子的接收。
Oviposition attractants are environmental cues that allow Culex gravid female mosquitoes to locate suitable sites for egg-laying and, therefore, may be exploited for environmentally friendly strategies for controlling mosquito populations. Naturally occurring skatole has been identified as an oviposition attractant for the Southern House mosquito, Culex quinquefasciatus. Previously, we identified in Cx. quinquefasciatus female antennae an olfactory receptor neuron (ORN) highly sensitive to skatole and an odorant-binding protein involved in the detection of this semiochemical. Here, we describe the characterization of an odorant receptor (OR), CquiOR10, which is narrowly tuned to skatole when expressed in the Xenopus oocyte system. Odorant-induced response profiles generated by heterologously expressed CquiOR10 suggest that this OR is expressed in the mosquito ORN sensitive to skatole. However, geranylacetone, which stimulates the antennal ORN, was not detected by CquiOR10-expressing oocytes, thus raising interesting questions about reception of oviposition attractants in mosquitoes.
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影响因子：
2.1
作者：
Barbosa RM;Regis L;Vasconcelos R;Leal WS
通讯作者：
Leal WS
影响因子：
3.7
作者：
Leal WS;Barbosa RM;Xu W;Ishida Y;Syed Z;Latte N;Chen AM;Morgan TI;Cornel AJ;Furtado A
通讯作者：
Furtado A
影响因子：
3.5
作者：
Syed, Zainulabeuddin;Leal, Walter S.
通讯作者：
Leal, Walter S.
影响因子：
3.7
作者：
Pelletier J;Hughes DT;Luetje CW;Leal WS
通讯作者：
Leal WS
DOI：
10.1073/pnas.0906932106
发表时间：
2009-11-03
影响因子：
11.1
作者：
Syed, Zainulabeuddin;Leal, Walter S.
通讯作者：
Leal, Walter S.