A high-performance neural prosthesis enabled by control algorithm design.
A high-performance neural prosthesis enabled by control algorithm design.
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DOI:
10.1038/nn.3265
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发表时间:
2012-12
影响因子:
25
通讯作者:
Shenoy, Krishna V.
中科院分区:
文献类型:
--
作者:
Gilja, Vikash;Nuyujukian, Paul;Chestek, Cindy A.;Cunningham, John P.;Yu, Byron M.;Fan, Joline M.;Churchland, Mark M.;Kaufman, Matthew T.;Kao, Jonathan C.;Ryu, Stephen I.;Shenoy, Krishna V.
Neural prostheses translate neural activity from the brain into control signals for guiding prosthetic devices, such as computer cursors and robotic limbs, and thus offer disabled patients greater interaction with the world. However, relatively low performance remains a critical barrier to successful clinical translation; current neural prostheses are considerably slower with less accurate control than the native arm. Here we present a new control algorithm, the recalibrated feedback intention-trained Kalman filter (ReFIT-KF), that incorporates assumptions about the nature of closed loop neural prosthetic control. When tested with rhesus monkeys implanted with motor cortical electrode arrays, the ReFIT-KF algorithm outperforms existing neural prostheses in all measured domains and halves acquisition time. This control algorithm permits sustained uninterrupted use for hours and generalizes to more challenging tasks without retraining. Using this algorithm, we demonstrate repeatable high performance for years after implantation across two monkeys, thereby increasing the clinical viability of neural prostheses.
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影响因子:
4
作者:
Chestek CA;Gilja V;Nuyujukian P;Foster JD;Fan JM;Kaufman MT;Churchland MM;Rivera-Alvidrez Z;Cunningham JP;Ryu SI;Shenoy KV
通讯作者:
Shenoy KV
影响因子:
4
作者:
McFarland DJ;Sarnacki WA;Wolpaw JR
通讯作者:
Wolpaw JR
DOI:
10.1016/j.neunet.2009.05.005
发表时间:
2009-11
期刊:
Neural networks : the official journal of the International Neural Network Society
影响因子:
--
作者:
Chase SM;Schwartz AB;Kass RE
通讯作者:
Kass RE
影响因子:
9.8
作者:
Ganguly K;Carmena JM
通讯作者:
Carmena JM
影响因子:
64.8
作者:
Hochberg, Leigh R.;Serruya, Mijail D.;Donoghue, John P.
通讯作者:
Donoghue, John P.