GeneSet2miRNA: finding the signature of cooperative miRNA activities in the gene lists.

GeneSet2miRNA: finding the signature of cooperative miRNA activities in the gene lists.
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DOI:
10.1093/nar/gkp313
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发表时间:
2009-07
影响因子:
14.9
通讯作者:
Mewes HW
Mewes HW
中科院分区:
生物学2区
文献类型:
--
作者:
Antonov AV;Dietmann S;Wong P;Lutter D;Mewes HW

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GeneSet2miRNA是第一个基于网络的工具,能够识别基因列表是否具有miRNA调控活性的签名。作为输入,GeneSet 2 miRNA接受基因列表。作为输出,提供了miRNA调控模型的列表。miRNA调控模型是一组miRNA(单个、成对、三联体或四联体),预测其调控提交列表中的重要基因子集。GeneSet2miRNA提供了一个用户友好的对话驱动的网页提交几个模式生物。GeneSet2miRNA可在http://mips.helmholtz-muenchen.de/proj/gene2mir/上免费获得。
GeneSet2miRNA is the first web-based tool which is able to identify whether or not a gene list has a signature of miRNA-regulatory activity. As input, GeneSet2miRNA accepts a list of genes. As output, a list of miRNA-regulatory models is provided. A miRNA-regulatory model is a group of miRNAs (single, pair, triplet or quadruplet) that is predicted to regulate a significant subset of genes from the submitted list. GeneSet2miRNA provides a user friendly dialog-driven web page submission available for several model organisms. GeneSet2miRNA is freely available at http://mips.helmholtz-muenchen.de/proj/gene2mir/.
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