Polymeric biomaterials for biophotonic applications.

Polymeric biomaterials for biophotonic applications.
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DOI:
10.1016/j.bioactmat.2018.07.001
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发表时间:
2018-12
影响因子:
18.9
通讯作者:
Yang J
Yang J
中科院分区:
工程技术1区
文献类型:
--
作者:
Shan D;Gerhard E;Zhang C;Tierney JW;Xie D;Liu Z;Yang J

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With the growing importance of optical techniques in medical diagnosis and treatment, there exists a pressing need to develop and optimize materials platform for biophotonic applications. Particularly, the design of biocompatible and biodegradable materials with desired optical, mechanical, chemical, and biological properties is required to enable clinically relevant biophotonic devices for translating in vitro optical techniques into in situ and in vivo use. This technological trend propels the development of natural and synthetic polymeric biomaterials to replace traditional brittle, nondegradable silica glass based optical materials. In this review, we present an overview of the advances in polymeric optical material development, optical device design and fabrication techniques, and the accompanying applications to imaging, sensing and phototherapy. Recent progress on the development of natural and synthetic polymeric optical biomaterials were reviewed. Advanced design and fabrication techniques for polymeric biomaterial-based biophotonic devices were discussed. Applications of bioimaging, biosensing, and phototherapy using polymeric biomaterial-based biophotonics were summarized.
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