Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers.
Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers.
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DOI：
10.1289/ehp.8182
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发表时间：
2006-05
影响因子：
10.4
通讯作者：
McCauley L
中科院分区：
文献类型：
--
作者：
Rothlein J;Rohlman D;Lasarev M;Phillips J;Muniz J;McCauley L
尽管旨在检查低水平长期接触农药可能对神经行为产生影响的研究有限，但我们对在工作和家庭环境中接触农药的农场工人的健康风险的了解正在迅速增加。我们测量了磷酸二烷基酯尿代谢物水平，从部分家庭中收集了环境灰尘样本，获取了工作实践信息，并对俄勒冈州的农场工人样本进行了神经行为测试。观察到尿甲基代谢物水平与总甲基有机磷酸盐（谷硫磷、亚胺硫磷、马拉硫磷）室内灰尘水平之间存在显着相关性。我们发现西班牙裔移民农场工人的神经行为表现低于非农业西班牙裔移民群体中观察到的神经行为表现，并且在农业工人样本中，尿液有机磷代谢物水平与某些神经行为测试中较差的表现之间存在正相关。这些发现为低水平农药暴露与神经行为表现缺陷之间的关联提供了越来越多的证据。
Our understanding of the health risks of farmworkers exposed to pesticides in their work and home environments is rapidly increasing, although studies designed to examine the possible neurobehavioral effects of low-level chronic pesticide exposure are limited. We measured dialkyl phosphate urinary metabolite levels, collected environmental dust samples from a subset of homes, obtained information on work practices, and conducted neurobehavioral tests on a sample of farmworkers in Oregon. Significant correlations between urinary methyl metabolite levels and total methyl organophosphate (azinphos-methyl, phosmet, malathion) house dust levels were observed. We found the neurobehavioral performance of Hispanic immigrant farmworkers to be lower than that observed in a nonagricultural Hispanic immigrant population, and within the sample of agricultural workers there was a positive correlation between urinary organophosphate metabolite levels and poorer performance on some neurobehavioral tests. These findings add to an increasing body of evidence of the association between low levels of pesticide exposure and deficits in neurobehavioral performance.
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影响因子：
10.4
作者：
Coronado GD;Thompson B;Strong L;Griffith WC;Islas I
通讯作者：
Islas I
影响因子：
4
作者：
LEWIS, RG;FORTMANN, RC;CAMANN, DE
通讯作者：
CAMANN, DE
影响因子：
4.9
作者：
Farahat, TM;Abdelrasoul, GM;Anger, WK
通讯作者：
Anger, WK
DOI：
10.1023/a:1013059211540
发表时间：
2002-01-01
期刊：
Journal of immigrant health
影响因子：
--
作者：
Napolitano, Marie;Lasarev, Michael;McCauley, Linda
通讯作者：
McCauley, Linda
影响因子：
8.3
作者：
Azaroff, LS
通讯作者：
Azaroff, LS