All-optical optoacoustic microscopy based on probe beam deflection technique.
All-optical optoacoustic microscopy based on probe beam deflection technique.
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DOI：
10.1016/j.pacs.2016.02.001
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发表时间：
2016-09
期刊：
影响因子：
7.9
通讯作者：
Oraevsky, Alexander A.
中科院分区：
文献类型：
--
作者：
Maswadi, Saher M.;Ibey, Bennett L.;Roth, Caleb C.;Tsyboulski, Dmitri A.;Beier, Hope T.;Glickman, Randolph D.;Oraevsky, Alexander A.
关键词：
光声 (OA) 显微镜使用基于探测光束偏转技术 (PBDT) 的全光学系统来检测激光诱导声信号，作为传统压电换能器的替代方案进行了研究。 PBDT 为 OA 显微镜提供了许多优势，包括 (i) 将激光激发能量有效耦合到通过探测激光束成像的样品，(ii) 将声波无失真地耦合到探测器，无需分离光学和声学路径，(iii) 高灵敏度和 (iv) 超宽带宽。由于 PBDT 中的光路不受阻碍，因此可以轻松实现衍射极限的横向分辨率。当前 PBDT 传感器的灵敏度为 22 μV/Pa，噪声等效压力 (NEP) 为 11.4 Pa，与光学微环谐振器和商用压电超声换能器的这些参数相当。通过成功解析心肌组织切片中的微米级细节，证明了当前原型 OA 显微镜的优点。
Optoacoustic (OA) microscopy using an all-optical system based on the probe beam deflection technique (PBDT) for detection of laser-induced acoustic signals was investigated as an alternative to conventional piezoelectric transducers. PBDT provides a number of advantages for OA microscopy including (i) efficient coupling of laser excitation energy to the samples being imaged through the probing laser beam, (ii) undistorted coupling of acoustic waves to the detector without the need for separation of the optical and acoustic paths, (iii) high sensitivity and (iv) ultrawide bandwidth. Because of the unimpeded optical path in PBDT, diffraction-limited lateral resolution can be readily achieved. The sensitivity of the current PBDT sensor of 22 μV/Pa and its noise equivalent pressure (NEP) of 11.4 Pa are comparable with these parameters of the optical micro-ring resonator and commercial piezoelectric ultrasonic transducers. Benefits of the present prototype OA microscope were demonstrated by successfully resolving micron-size details in histological sections of cardiac muscle.
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影响因子：
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DOI：
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