Body composition measurement for the preterm neonate: using a clinical utility framework to translate research tools into clinical care.

Body composition measurement for the preterm neonate: using a clinical utility framework to translate research tools into clinical care.
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DOI:
10.1038/s41372-022-01529-9
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发表时间:
2022-11
影响因子:
2.9
通讯作者:
Belfort, Mandy B.
Belfort, Mandy B.
中科院分区:
医学3区
文献类型:
--
作者:
Bell, Katherine A.;Ramel, Sara E.;Robinson, Daniel T.;Wagner, Carol L.;Scottoline, Brian;Belfort, Mandy B.

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身体成分分析,以区分脂肪质量和无脂肪质量是一个既定的研究方法,以评估营养状况。在新生儿医学中,早产儿的身体组成与后期的健康结果有关,包括神经发育和心脏代谢健康。越来越多的证据表明,无脂体重是营养状况的一个指标,再加上可用的测试方法,是可行的早产儿使用,提高了在新生儿重症监护病房(NICU)设置测量身体成分的兴趣。在本文中,我们使用的概念,临床实用性的一种新的方法,在当前的标准护理的附加值,作为一个框架,评估现有的身体成分的方法与潜在的临床应用于早产儿。我们还使用这个框架来确定剩余的知识差距,并优先考虑努力,以促进我们对NICU中临床导向的身体成分测试的理解。
Body composition analysis to distinguish between fat mass and fat-free mass is an established research approach to assess nutritional status. Within neonatal medicine, preterm infant body composition is linked with later health outcomes including neurodevelopment and cardiometabolic health. Mounting evidence establishing fat-free mass as an indicator of nutritional status, coupled with the availability of testing approaches that are feasible to use in preterm infants, have enhanced interest in measuring body composition in the neonatal intensive care unit (NICU) setting. In this paper, we use the concept of clinical utility—the added value of a new methodology over current standard care—as a framework for assessing several existing body composition methodologies with potential for clinical application to preterm neonates. We also use this framework to identify remaining knowledge gaps and prioritize efforts to advance our understanding of clinically-oriented body composition testing in the NICU.
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