Just say "I don't": lack of concordance between teen report and biological measures of drug use.
Just say "I don't": lack of concordance between teen report and biological measures of drug use.
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DOI：
10.1542/peds.2009-3059
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发表时间：
2010-11
期刊：
影响因子：
8
通讯作者：
Sokol RJ
中科院分区：
文献类型：
--
作者：
Delaney-Black V;Chiodo LM;Hannigan JH;Greenwald MK;Janisse J;Patterson G;Huestis MA;Ager J;Sokol RJ
对青少年非法药物使用流行率的估计通常来自保密或匿名的自我报告。虽然比较青少年自我报告与生物测量的数据有限，但成人研究发现了不同程度的低报。在一个纵向队列中，对400多名高危城市青少年和父母进行了可卡因、阿片类药物和大麻的头发分析，并将其与青少年自我和父母报告的青少年药物使用情况进行了比较。青少年和父母都大大低估了最近青少年可卡因和阿片类药物的使用。然而，与父母相比，青少年更有可能否认生物标记验证的可卡因使用。与自我报告相比，青少年样本（头发）识别可卡因使用的可能性高出52倍。父母的头发分析可卡因和阿片类药物的使用分别为6.5倍和5.5倍，更有可能表明药物使用比父母的自我报告。尽管参与者知道“保密证书”保护青少年和成年参与者，并且生物样本将进行药物测试，但自我报告和生物测定之间缺乏一致性。这些发现证实了之前关于成年人少报自己吸毒的报道，同时扩展了我们对青少年自我承认吸毒的理解。青少年自我或父母报告的青少年药物使用与生物标志物之间缺乏一致性证实了我们的担忧，即青少年和父母报告的青少年药物使用是有限的，至少对于高风险城市环境中的青少年来说。当卫生保健提供者、研究人员和公共卫生机构试图估计青少年吸毒流行率时，必须考虑自我或父母报告以外的确定方法。
Prevalence estimates of illicit drug use by teens are typically generated from confidential or anonymous self-report. While data comparing teen self-report with biological measures are limited, adult studies identify varying degrees of under-reporting. Hair analyses for cocaine, opiates and marijuana were compared to confidential teen self- and parent-reported teen drug use in a longitudinal cohort of >400 high-risk urban teens and parents. Both teens and parents substantially underreported recent teen cocaine and opiate use. However, compared with parents, teens were more likely to deny biomarker-verified cocaine use. Teen specimens (hair) were 52 times more likely to identify cocaine use compared with self-report. Parent hair analyses for cocaine and opiate use were 6.5 times and 5.5 times, respectively, more likely to indicate drug use than were parental self-report. The lack of concordance between self-report and bioassay occurred despite participant’s knowledge that a “certificate of confidentiality” protected both teen and adult participants, and that the biological specimens would be tested for drugs. These findings confirm prior reports of adult under-reporting of their own drug use while extending our understanding of teen’s self-admitted drug use. The lack of concordance between teen self- or parent-reported teen drug use and biomarkers confirm our concerns that both teen- and parent-reported teen drug use is limited, at least for youth in high-risk urban settings. Methods of ascertainment other than self- or parent-report must be considered when health care providers, researchers and public health agencies attempt to estimate teen drug-use prevalence.
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影响因子：
4.4
作者：
Bowling, A
通讯作者：
Bowling, A
影响因子：
4.2
作者：
Ensminger, ME;Anthony, JC;McCord, J
通讯作者：
McCord, J
影响因子：
2.2
作者：
Mieczkowski, T
通讯作者：
Mieczkowski, T
影响因子：
2.8
作者：
MIECZKOWSKI, T;BARZELAY, D;WISH, E
通讯作者：
WISH, E
影响因子：
1.9
作者：
LANDIS, JR;KOCH, GG
通讯作者：
KOCH, GG