Physical Activity of Patients with Chronic Schizophrenia and Related Clinical Factors.

Physical Activity of Patients with Chronic Schizophrenia and Related Clinical Factors.
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DOI:
10.30773/pi.2018.04.15.1
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发表时间:
2018-08
影响因子:
2.7
通讯作者:
Ryu S
Ryu S
中科院分区:
医学4区
文献类型:
--
作者:
Lee SH;Kim G;Kim CE;Ryu S

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本研究旨在探讨慢性精神分裂症患者低体力活动(PA)的临床因素。采用国际体力活动问卷简表(iPAQ-SF)对50例门诊慢性精神分裂症患者进行PA测定。分别采用简明精神病评定量表(BPRS-18)、总体功能评定量表(GAF)和药物所致锥体外系症状量表(DIEPSS)评定患者的心理病理、心理社会功能和锥体外系症状。我们研究了“不活跃”、“低活动量”和“增进健康体力活动”组在这些临床变量上的差异。采用线性回归分析精神分裂症患者血浆PA水平降低的临床因素。受试者平均每周花费130.18±238.89分钟进行中等强度的PA,其中只有26%的人达到了推荐的每周至少150分钟的中等强度PA的指导原则。非活动组的BPRS-18和DIEPSS评分显著高于其他组,而GAF评分显著低于其他组。线性回归分析显示,DIEPSS评分独立地解释了PA总量(p=0.001)和久坐时间(p=0.028)。这项研究提供了初步证据,表明锥体外系症状可能是精神分裂症患者PA的主要障碍。
This study aimed to investigate clinical factors contributing to the low physical activity (PA) of patients with chronic schizophrenia. PA was measured in 50 outpatients with chronic schizophrenia using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Psychopathology, psychosocial functioning, and extrapyramidal symptoms were assessed using the 18 item-Brief Psychiatric Rating Scale (BPRS-18), Global Assessment of Functioning (GAF), and Drug-Induced Extrapyramidal Symptom Scale (DIEPSS), respectively. We examined differences in these clinical variables between “inactive,” “minimally active,” and “health enhancing physical activity” groups. Linear regression analysis was used to examine the clinical factors explaining low PA levels in patients with schizophrenia. Subjects spent an average of 130.18±238.89 min/wk on moderate/vigorous-intensity PA and only 26% of them met the recommended PA guideline of 150 minutes of at least moderate PA per week. The inactive group showed significantly higher BPRS-18 and DIEPSS scores, and a lower GAF score than the other groups. Linear regression analysis showed that DIEPSS scores independently explained the amount of total PA (p=0.001) and time spent being sedentary (p=0.028). This study provides preliminary evidence that extrapyramidal symptoms could be a major impediment to the PA of patients with schizophrenia.
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