Hippocampal brain-network coordination during volitional exploratory behavior enhances learning.
Hippocampal brain-network coordination during volitional exploratory behavior enhances learning.
复制标题
DOI：
10.1038/nn.2693
复制
发表时间：
2011-01
影响因子：
25
通讯作者：
Cohen, Neal J.
中科院分区：
文献类型：
--
作者：
Voss, Joel L.;Gonsalves, Brian D.;Federmeier, Kara D.;Tranel, Daniel;Cohen, Neal J.
学习过程中的探索行为决定了学习什么和什么时候学习，有助于优化随后的记忆表现。为了阐明探索行为的认知和神经决定因素，我们操纵了受试者对移动窗口位置的控制程度。我们的行为学、神经心理学和神经影像学数据表明，意志控制有益于记忆表现，并且与以海马体为中心的大脑网络有关。海马体和其他区域之间相关活动的增加与记忆的特定方面有关，这表明意志控制通过海马体优化了专门神经系统之间的相互作用。因此，记忆是一个与行为有着内在联系的主动过程。此外，大脑结构通常被视为记忆编码的被动参与者（例如，海马体）实际上是一个主动网络的一部分，它在展开时动态地控制行为。
Exploratory behaviors during learning determine what is studied and when, helping to optimize subsequent memory performance. We manipulated how much control subjects had over the position of a moving window through which they studied objects and their locations, in order to elucidate the cognitive and neural determinants of exploratory behaviors. Our behavioral, neuropsychological, and neuroimaging data indicate volitional control benefits memory performance, and is linked to a brain network centered on the hippocampus. Increases in correlated activity between the hippocampus and other areas were associated with specific aspects of memory, suggesting that volitional control optimizes interactions among specialized neural systems via the hippocampus. Memory is therefore an active process intrinsically linked to behavior. Furthermore, brain structures typically seen as passive participants in memory encoding (e.g., the hippocampus) are actually part of an active network that controls behavior dynamically as it unfolds.
登录
查看更多内容
影响因子：
19.9
作者：
Epstein, Russell A.
通讯作者：
Epstein, Russell A.
影响因子：
3.2
作者：
Chua, Elizabeth F.;Schacter, Daniel L.;Sperling, Reisa A.
通讯作者：
Sperling, Reisa A.
DOI：
10.1080/13803390590949287
发表时间：
2006-05-01
影响因子：
2.2
作者：
Allen, JS;Tranel, D;Damasio, H
通讯作者：
Damasio, H
影响因子：
9.2
作者：
Harman, KL;Humphrey, GK;Goodale, MA
通讯作者：
Goodale, MA
影响因子：
56.9
作者：
COHEN, NJ;SQUIRE, LR
通讯作者：
SQUIRE, LR