Environmental sources of prion transmission in mule deer.
Environmental sources of prion transmission in mule deer.
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DOI:
10.3201/eid1006.040010
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发表时间:
2004-06
影响因子:
11.8
通讯作者:
Wolfe LL
中科院分区:
文献类型:
--
作者:
Miller MW;Williams ES;Hobbs NT;Wolfe LL
Whether transmission of the chronic wasting disease (CWD) prion among cervids requires direct interaction with infected animals has been unclear. We report that CWD can be transmitted to susceptible animals indirectly, from environments contaminated by excreta or decomposed carcasses. Under experimental conditions, mule deer (Odocoileus hemionus) became infected in two of three paddocks containing naturally infected deer, in two of three paddocks where infected deer carcasses had decomposed in situ ≈1.8 years earlier, and in one of three paddocks where infected deer had last resided 2.2 years earlier. Indirect transmission and environmental persistence of infectious prions will complicate efforts to control CWD and perhaps other animal prion diseases.
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影响因子:
1.3
作者:
WILLIAMS, ES;YOUNG, S
通讯作者:
YOUNG, S
影响因子:
2.2
作者:
Wilesmith, JW
通讯作者:
Wilesmith, JW
影响因子:
3.5
作者:
Brayton, KA;O'Rourke, KI;Knowles, DP
通讯作者:
Knowles, DP
影响因子:
56.9
作者:
Kao, RR;Gravenor, MB;McLean, AR
通讯作者:
McLean, AR
影响因子:
1.3
作者:
Miller, MW;Wild, MA;Williams, ES
通讯作者:
Williams, ES