Effect of intraspecimen spatial variation in tissue mineral density on the apparent stiffness of trabecular bone.
Effect of intraspecimen spatial variation in tissue mineral density on the apparent stiffness of trabecular bone.
复制标题
组织矿物质密度的标本内空间变化对小梁骨表观刚度的影响。
DOI:
10.1115/1.4029178
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发表时间:
2015
期刊:
影响因子:
--
通讯作者:
Kazakia,GalateiaJ
中科院分区:
文献类型:
--
作者:
Kaynia,Narges;Soohoo,Elaine;Keaveny,TonyM;Kazakia,GalateiaJ
This study investigated the effects of intraspecimen variations in tissue mineral density (TMD) on the apparent-level stiffness of human trabecular bone. High-resolution finite element (FE) models were created for each of 12 human trabecular bone specimens, using both microcomputed tomography (μCT) and “gold-standard” synchrotron radiation μCT (SRμCT) data. Our results confirm that incorporating TMD spatial variation reduces the calculated apparent stiffness compared to homogeneous TMD models. This effect exists for both μCT- and SRμCT-based FE models, but is exaggerated in μCT-based models. This study provides a direct comparison of μCT to SRμCT data and is thereby able to conclude that the influence of including TMD heterogeneity is overestimated in μCT-based models.
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DOI:
--
发表时间:
1981
期刊:
AJR. American journal of roentgenology
影响因子:
--
作者:
David J. Goodenough;K. Weaver;David O. Davis;S. LaFalce
通讯作者:
S. LaFalce
影响因子:
4.1
作者:
Yao, Wei;Cheng, Zhiqiang;Lane, Nancy E.
通讯作者:
Lane, Nancy E.
DOI:
10.1080/10255842.2011.581236
发表时间:
2012-01-01
影响因子:
1.6
作者:
Gross, Thomas;Pahr, Dieter H.;Zysset, Philippe K.
通讯作者:
Zysset, Philippe K.
影响因子:
2.4
作者:
Renders, G. A. P.;Mulder, L.;van Eijden, T. M. G. J.
通讯作者:
van Eijden, T. M. G. J.
影响因子:
1.9
作者:
David B. Burr
通讯作者:
David B. Burr