Legacies of salient environmental experiences-insights from chemosensation.

Legacies of salient environmental experiences-insights from chemosensation.
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从化学一致化的显着环境经历的遗产。

DOI:
10.1093/chemse/bjae002
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发表时间:
2024-01-01
期刊:
影响因子:
3.5
通讯作者:
--
中科院分区:
心理学4区
文献类型:
--
作者:

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父母环境深刻影响后代的生理学,生物学和神经生物学的证据已经在文献中积累。最近的努力,以了解这一现象及其潜在的机制,试图使用物种,如啮齿动物和昆虫,以模拟多代遗传的父母的经验,如压力和营养暴露。从这些研究中,我们认识到,父母暴露于显著的环境经验会影响大脑发育的节奏,对压力的激素反应,以及控制后代对压力的细胞反应的基因表达。最近的研究使用化学感应暴露已经成为一个强大的工具,揭示了后代如何受到父母所处环境的影响。特别关注利用这种突出的化学感受经验的研究,本文综述了我们目前对后代化学感受遗产遗传的概念,原因和后果的理解,以及这一领域的调查如何告知父母的经验如何影响后代生物学的更大图景。
Evidence for parental environments profoundly influencing the physiology, biology, and neurobiology of future generations has been accumulating in the literature. Recent efforts to understand this phenomenon and its underlying mechanisms have sought to use species like rodents and insects to model multi-generational legacies of parental experiences like stress and nutritional exposures. From these studies, we have come to appreciate that parental exposure to salient environmental experiences impacts the cadence of brain development, hormonal responses to stress, and the expression of genes that govern cellular responses to stress in offspring. Recent studies using chemosensory exposure have emerged as a powerful tool to shed new light on how future generations come to be influenced by environments to which parents are exposed. With a specific focus on studies that have leveraged such use of salient chemosensory experiences, this review synthesizes our current understanding of the concept, causes, and consequences of the inheritance of chemosensory legacies by future generations and how this field of inquiry informs the larger picture of how parental experiences can influence offspring biology.
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