Air Pollution Is Associated with COVID-19 Incidence and Mortality in Vienna, Austria.

Air Pollution Is Associated with COVID-19 Incidence and Mortality in Vienna, Austria.
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DOI:
10.3390/ijerph17249275
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发表时间:
2020-12-11
影响因子:
--
通讯作者:
Kundi M
Kundi M
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Hutter HP;Poteser M;Moshammer H;Lemmerer K;Mayer M;Weitensfelder L;Wallner P;Kundi M

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我们确定了空气污染对COVID-19相关死亡率和确诊病例发生率的影响,分析了感染病例数和结果与维也纳23个区人口前一年空气污染数据的相关性。当第一例COVID-19病例被诊断出来时,一个地区的风险时间就开始了。高暴露水平被定义为生活在二氧化氮(NO2)和/或颗粒物(PM10)平均浓度(2019年)高于所有地区的上四分位数(分别为30和20 µg/m3)的地区。个别地区的总人口被追踪至确诊或死于COVID-19,或直至2020年4月21日(以先发生者为准)。在控制了65岁及以上人口的百分比、外国人和具有大学学位的人的百分比、失业率和人口密度后,进行了考克斯比例风险回归。PM10和NO2与COVID-19诊断风险显著正相关(风险比(HR)分别为1.44和1.16)。NO2也与COVID-19死亡显著相关(HR = 1.72)。即使在一个城市内,空气污染水平较高也会对COVID-19风险产生不利影响。
We determined the impact of air pollution on COVID-19-related mortality and reported-case incidence, analyzing the correlation of infection case numbers and outcomes with previous-year air pollution data from the populations of 23 Viennese districts. Time at risk started in a district when the first COVID-19 case was diagnosed. High exposure levels were defined as living in a district with an average (year 2019) concentration of nitrogen dioxide (NO2) and/or particulate matter (PM10) higher than the upper quartile (30 and 20 µg/m3, respectively) of all districts. The total population of the individual districts was followed until diagnosis of or death from COVID-19, or until 21 April 2020, whichever came first. Cox proportional hazard regression was performed after controlling for percentage of population aged 65 and more, percentage of foreigners and of persons with a university degree, unemployment rate, and population density. PM10 and NO2 were significantly and positively associated with the risk of a COVID-19 diagnosis (hazard ratio (HR) = 1.44 and 1.16, respectively). NO2 was also significantly associated with death from COVID-19 (HR = 1.72). Even within a single city, higher levels of air pollution are associated with an adverse impact on COVID-19 risk.
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