Serotonin modulates behavioral reactions to unfairness.
Serotonin modulates behavioral reactions to unfairness.
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DOI:
10.1126/science.1155577
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发表时间:
2008-06-27
期刊:
影响因子:
--
通讯作者:
Robbins TW
中科院分区:
文献类型:
--
作者:
Crockett MJ;Clark L;Tabibnia G;Lieberman MD;Robbins TW
Serotonin (5-HT) has long been implicated in social behavior and impulsivity, but the mechanisms through which it modulates self-control remain unclear. We observed the effects of manipulating 5-HT function on behavior in the Ultimatum Game, where players must decide whether to accept or reject fair or unfair monetary offers from another player. Participants with depleted 5-HT levels rejected a greater proportion of unfair, but not fair offers, without showing changes in mood, fairness judgments, basic reward processing or response inhibition. Our results suggest that 5-HT plays a critical role in regulating emotion during social decision-making.
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