Exploring the Relationship between Medical Research Literacy and Respondents' Expressed Likelihood to Participate in a Clinical Trial.

Exploring the Relationship between Medical Research Literacy and Respondents' Expressed Likelihood to Participate in a Clinical Trial.
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探索医学研究素养与受访者表达的参与临床试验可能性之间的关系。

DOI:
10.3390/ijerph192215168
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发表时间:
2022-11-17
影响因子:
--
通讯作者:
Edwards, Dorothy Farrar
Edwards, Dorothy Farrar
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Dykema, Jennifer;Jones, Cameron P.;Garbarski, Dana;Farias, Mia;Edwards, Dorothy Farrar

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医学研究素养(MRL)是健康素养的一个方面,衡量一个人对知情同意和参与医学研究的其他方面的理解。虽然目前对MRL的研究有限,但有理由相信MRL可能与参与医学研究的意愿有关。我们使用来自调查受访者的种族平衡样本(n = 410)的数据:(1)分析MRL评分如何因受访者的社会人口统计学特征而变化;(2)检查MRL如何与受访者表示参与临床试验的可能性相关;(3)提供MRL测量的考虑因素。结果表明,不同种族或性别的MRL评分没有差异;年轻(p < 0.05)和受教育程度较高(p < 0.001)的个体的MRL评分显著较高。此外,较高的MRL评分与参与临床试验的表达可能性显著降低相关。此外,MRL量表包括真实和虚假陈述,分析表明这些陈述与结果的关系存在显著差异。总而言之,研究结果表明,需要进一步的研究来了解MRL,以及它如何与研究参与相关的社会人口特征相关,并可以有效地测量。
Medical research literacy (MRL) is a facet of health literacy that measures a person’s understanding of informed consent and other aspects of participation in medical research. While existing research on MRL is limited, there are reasons to believe MRL may be associated with a willingness to participate in medical research. We use data from a racially balanced sample of survey respondents (n = 410): (1) to analyze how MRL scores vary by respondents’ socio-demographic characteristics; (2) to examine how MRL relates to respondents’ expressed likelihood to participate in a clinical trial; and (3) to provide considerations on the measurement of MRL. The results indicate no differences in MRL scores by race or gender; younger (p < 0.05) and more educated (p < 0.001) individuals have significantly higher MRL scores. Further, higher MRL scores are associated with significantly lower levels of expressed likelihood to participate in a clinical trial. Additionally, the MRL scale included both true and false statements, and analyses demonstrate significant differences in how these relate to outcomes. Altogether, the results signal that further research is needed to understand MRL and how it relates to socio-demographic characteristics associated with research participation and can be measured effectively.
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