Wheel running decreases the positive reinforcing effects of heroin.
Wheel running decreases the positive reinforcing effects of heroin.
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DOI:
10.1016/s1734-1140(12)70891-5
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发表时间:
2012
影响因子:
4.4
通讯作者:
Pitts, Elizabeth G.
中科院分区:
文献类型:
--
作者:
Smith, Mark A.;Pitts, Elizabeth G.
The purpose of this study was to examine the effects of voluntary wheel running on the positive reinforcing effects of heroin in rats with an established history of drug self-administration. Rats were assigned to sedentary (no wheel) and exercise (wheel) conditions and trained to self-administer cocaine under positive reinforcement contingencies. Rats acquiring cocaine self-administration were then tested with various doses of heroin during daily test sessions. Sedentary rats self-administered more heroin than exercising rats, and this effect was greatest at low and moderate doses of heroin. These data suggest that voluntary wheel running decreases the positive reinforcing effects of heroin.
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DOI:
10.1046/j.1365-201x.1997.00118.x
发表时间:
1997-04-01
期刊:
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子:
--
作者:
Meeusen, R;Smolders, I;Michotte, Y
通讯作者:
Michotte, Y
DOI:
10.1124/jpet.108.139196
发表时间:
2008-09-01
影响因子:
3.5
作者:
Cooper, Ziva D.;Truong, Yen Nhu-Thi;Woods, James H.
通讯作者:
Woods, James H.
影响因子:
1.9
作者:
Kanarek, Robin B.;D'Anci, Kristen E.;Jurdak, Nicole;Mathes, Wendy Foulds
通讯作者:
Mathes, Wendy Foulds
影响因子:
--
作者:
HOFFMANN, P;TERENIUS, L;THOREN, P
通讯作者:
THOREN, P
影响因子:
4.2
作者:
Fisher, BE;Petzinger, GM;Jakowec, MW
通讯作者:
Jakowec, MW