Reduced spontaneous but relatively normal deliberate vicarious representations in psychopathy.
Reduced spontaneous but relatively normal deliberate vicarious representations in psychopathy.
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DOI：
10.1093/brain/awt190
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发表时间：
2013-08
期刊：
影响因子：
--
通讯作者：
Keysers C
中科院分区：
文献类型：
--
作者：
Meffert H;Gazzola V;den Boer JA;Bartels AA;Keysers C
精神病是一种人格障碍，与严重缺乏同理心有关。神经科学家将共情及其个体间差异与参与者在观察他人行为、情绪和感觉时激活与自己行为、情绪和感觉相关的大脑区域的强烈程度联系起来。在这里，我们比较了18名精神病罪犯和26名对照者在观看情感手部互动的视频片段和经历类似互动时的大脑活动。在观看视频片段时，参与体验这些互动的大脑区域没有像患者组那样自发地强烈激活。然而，当我们特别指导参与者感受视频中的演员时，这种组间差异明显减少。我们的研究结果表明，精神病并不是简单的替代激活能力的丧失，而是自发性替代激活的减少与相对正常的有意识的替代激活共存。
Psychopathy is a personality disorder associated with a profound lack of empathy. Neuroscientists have associated empathy and its interindividual variation with how strongly participants activate brain regions involved in their own actions, emotions and sensations while viewing those of others. Here we compared brain activity of 18 psychopathic offenders with 26 control subjects while viewing video clips of emotional hand interactions and while experiencing similar interactions. Brain regions involved in experiencing these interactions were not spontaneously activated as strongly in the patient group while viewing the video clips. However, this group difference was markedly reduced when we specifically instructed participants to feel with the actors in the videos. Our results suggest that psychopathy is not a simple incapacity for vicarious activations but rather reduced spontaneous vicarious activations co-existing with relatively normal deliberate counterparts.
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影响因子：
4.3
作者：
BLAIR, RJR;SELLARS, C;JONES, L
通讯作者：
JONES, L
DOI：
10.1111/j.1749-6632.2010.05445.x
发表时间：
2010-01-01
期刊：
YEAR IN COGNITIVE NEUROSCIENCE 2010
影响因子：
--
作者：
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通讯作者：
Adolphs, Ralph
影响因子：
5.7
作者：
de Oliveira-Souza, Ricardo;Hare, Robert D.;Moll, Jorge
通讯作者：
Moll, Jorge
影响因子：
9.2
作者：
Dinstein, Ilan;Thomas, Cibu;Heeger, David J.
通讯作者：
Heeger, David J.
影响因子：
3.1
作者：
Caspers, Svenja;Eickhoff, Simon B.;Amunts, Katrin
通讯作者：
Amunts, Katrin