Equine arteritis virus: an overview.

Equine arteritis virus: an overview.
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DOI:
10.1016/0007-1935(92)90044-2
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发表时间:
1992-05
期刊:
The British veterinary journal
影响因子:
--
通讯作者:
Chirnside ED
Chirnside ED
中科院分区:
其他
文献类型:
--
作者:
Chirnside ED

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呼吸道疾病马病毒性动脉炎的病原体是一种小的单链RNA病毒,其基因组结构和复制策略与冠状病毒和圆环病毒相关。马感染的临床症状差异很大,严重感染可导致妊娠马流产。受感染的马一般恢复良好,但种马可能成为马动脉炎病毒(EAV)的精液脱落者。这些载体种马在EAV的传播和延续中发挥着重要作用。现有的实验室测试可以检测病毒和马对感染的免疫反应。然而,疫苗目前在英国尚未获得许可,以对抗病毒性动脉炎,由于欧洲立法的变化,其发病率可能会增加。
The causative agent of the respiratory disease equine viral arteritis is a small, single-stranded RNA virus with a genome organization and replication strategy related to that of coronaviruses and toroviruses. Clinical signs of infection in horses vary widely and severe infection can lead to pregnant mares aborting. Infected horses generally make good recoveries but stallions may become semen shedders of equine arteritis virus (EAV). These carrier stallions play an important role in the dissemination and perpetuation of EAV. Laboratory tests exist to detect virus and the equine immune response to infection. However, vaccines are not currently licensed in the UK to combat viral arteritis, the incidence of which may increase due to changes in European legislation.
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