Working towards an exegesis for lipids in biology.

Working towards an exegesis for lipids in biology.
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DOI:
10.1038/nchembio0909-602
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发表时间:
2009-09
影响因子:
14.8
通讯作者:
Murphy, Robert C.
Murphy, Robert C.
中科院分区:
生物学1区
文献类型:
--
作者:
Brown, H. Alex;Murphy, Robert C.

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作为一个领域,脂质组学还处于起步阶段,但它已经开始以多种方式影响脂质生物化学。与其他组学技术一样,该领域受到分析化学进步的推动,特别是质谱法。在脂质生物化学复兴的核心,系统生物学被用于定义细胞脂质组,建立代谢相互联系的全面图景,发现新的分子物种,并确定脂质如何调节生物功能。
As a field, lipidomics is in its infancy, yet it has already begun to influence lipid biochemistry in myriad ways. As with other omic technologies, the field is driven by advances in analytical chemistry, particularly by mass spectrometry. At the heart of a renaissance in lipid biochemistry, systems biology is being used to define the cellular lipome, build a comprehensive picture of metabolic interconnections, discover new molecular species and determine how lipids modulate biological functions.
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