Characterization of human oral tissues based on quantitative analysis of optical coherence tomography images
Characterization of human oral tissues based on quantitative analysis of optical coherence tomography images
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基于光学相干断层扫描图像定量分析的人体口腔组织表征
DOI：
10.1117/12.2253362
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发表时间：
2017
影响因子：
3.5
通讯作者：
Aditya Tadinada
中科院分区：
文献类型：
--
作者：
H. Salehi;A. Kósa;M. Mahdian;S. Moslehpour;H. Alnajjar;Aditya Tadinada
在本文中，使用光学相干断层扫描（OCT）对五种类型的组织（人牙釉质、人皮质骨、人小梁骨、肌肉组织和脂肪组织）进行离体成像。样品被制成 5 x 5 x 3 毫米（宽 x 长 x 高）的块。 OCT成像系统是扫频源OCT系统，工作波长范围为1250 nm至1360 nm，平均功率为18 mW，扫描速率为50至100 kHz。将成像探头放置在 2 x 2 cm 稳定装置的顶部，以与样品保持标准距离。从每种类型的组织中获得十个图像样本。为了获取不均匀性最小的图像，在不同点进行多次成像。基于观察到的软组织和硬组织OCT图像之间的纹理差异，从OCT图像中定量提取空间和光谱特征。计算从 0 度到 90 度角度的 Radon 变换，对所有角度进行平均，归一化为统一峰值，然后用高斯函数进行拟合。 OCT 图像的空间频率分量的平均绝对值被视为特征，其中对 OCT 图像进行二维快速傅里叶变换（FFT）。这些 OCT 特征可以可靠地区分一系列硬组织和软组织，对于协助牙医对口腔组织进行体内评估和早期检测组织病理变化非常有价值。
In this paper, five types of tissues, human enamel, human cortical bone, human trabecular bone, muscular tissue, and fatty tissue were imaged ex vivo using optical coherence tomography (OCT). The specimens were prepared in blocks of 5 x 5 x 3 mm (width x length x height). The OCT imaging system was a swept source OCT system operating at wavelengths ranging between 1250 nm and 1360 nm with an average power of 18 mW and a scan rate of 50 to 100 kHz. The imaging probe was placed on top of a 2 x 2 cm stabilizing device to maintain a standard distance from the samples. Ten image samples from each type of tissue were obtained. To acquire images with minimum inhomogeneity, imaging was performed multiple times at different points. Based on the observed texture differences between OCT images of soft and hard tissues, spatial and spectral features were quantitatively extracted from the OCT images. The Radon transform from angles of 0 deg to 90 deg was computed, averaged over all the angles, normalized to peak at unity, and then fitted with Gaussian function. The mean absolute values of the spatial frequency components of the OCT image were considered as a feature, where 2-D fast Fourier transform (FFT) was done to OCT images. These OCT features can reliably differentiate between a range of hard and soft tissues, and could be extremely valuable in assisting dentists for in vivo evaluation of oral tissues and early detection of pathologic changes in tissues.
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影响因子：
3.4
作者：
Wang, Tianheng;Nandy, Sreyankar;Zhu, Quing
通讯作者：
Zhu, Quing
估计任何边界形状的浑浊介质的光扩散方程的闭合解的方法。
DOI：
10.1364/josaa.33.000205
发表时间：
2016
期刊：
Journal of the Optical Society of America. A, Optics, image science, and vision
影响因子：
--
作者：
Alqasemi,Umar;Salehi,HassanS;Zhu,Quing
通讯作者：
Zhu,Quing
影响因子：
3.5
作者：
Matheny, ES;Hanna, NM;Brenner, M
通讯作者：
Brenner, M
影响因子：
3.4
作者：
Salehi, Hassan S.;Wang, Tianheng;Zhu, Quing
通讯作者：
Zhu, Quing