A Status Review on Health-Promoting Properties and Global Regulation of Essential Oils.

A Status Review on Health-Promoting Properties and Global Regulation of Essential Oils.
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DOI:
10.3390/molecules28041809
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发表时间:
2023-02-14
期刊:
影响因子:
4.6
通讯作者:
Obaid, Reyad Shaker
Obaid, Reyad Shaker
中科院分区:
化学2区
文献类型:
--
作者:
Osaili, Tareq M.;Dhanasekaran, Dinesh Kumar;Zeb, Falak;Faris, MoezAlIslam E.;Naja, Farah;Radwan, Hadia;Ismail, Leila Cheikh;Hasan, Hayder;Hashim, Mona;Obaid, Reyad Shaker

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自古以来,精油(EO)就以其对许多健康问题的治疗潜力而闻名。最近的研究表明,EOs可能有助于调节和调制各种生物标志物和细胞通路,这些生物标志物和细胞通路负责代谢健康以及许多疾病的发展,包括癌症、肥胖症、糖尿病、心血管疾病和细菌感染。在代谢功能障碍甚至感染期间,免疫系统变得受损并释放促炎细胞因子,导致严重的健康后果。来自水果、蔬菜和药用植物的具有不同化学组成的EO中存在的生物活性化合物(特别是萜类和苯丙素类)通过抗炎、抗氧化、抗癌和抗微生物特性赋予针对这些代谢和感染性疾病的保护。在这篇综述中,我们强调了一些有针对性的生理和细胞作用,通过这些作用,EO可能表现出抗炎,抗癌和抗微生物的特性。此外,已经观察到,来自特定植物来源的EO可以在预防肥胖、糖尿病、高血压、血脂异常、微生物感染和增加母乳产量方面发挥重要作用,沿着心脏、肝脏和大脑健康的改善。本文就其生物活性及其治疗作用的研究现状作一综述。然而,关于EO的健康益处,规范EO的剂量和使用以减少其不良健康影响是非常重要的。因此,我们指出,一些国家有自己的监管机构,而另一些国家则遵循世卫组织和粮农组织关于使用EO的标准和立法。
Since ancient times, essential oils (EOs) have been known for their therapeutic potential against many health issues. Recent studies suggest that EOs may contribute to the regulation and modulation of various biomarkers and cellular pathways responsible for metabolic health as well as the development of many diseases, including cancer, obesity, diabetes, cardiovascular diseases, and bacterial infections. During metabolic dysfunction and even infections, the immune system becomes compromised and releases pro-inflammatory cytokines that lead to serious health consequences. The bioactive compounds present in EOs (especially terpenoids and phenylpropanoids) with different chemical compositions from fruits, vegetables, and medicinal plants confer protection against these metabolic and infectious diseases through anti-inflammatory, antioxidant, anti-cancer, and anti-microbial properties. In this review, we have highlighted some targeted physiological and cellular actions through which EOs may exhibit anti-inflammatory, anti-cancer, and anti-microbial properties. In addition, it has been observed that EOs from specific plant sources may play a significant role in the prevention of obesity, diabetes, hypertension, dyslipidemia, microbial infections, and increasing breast milk production, along with improvements in heart, liver, and brain health. The current status of the bioactive activities of EOs and their therapeutic effects are covered in this review. However, with respect to the health benefits of EOs, it is very important to regulate the dose and usage of EOs to reduce their adverse health effects. Therefore, we specified that some countries have their own regulatory bodies while others follow WHO and FAO standards and legislation for the use of EOs.
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