Concerted transpositions of mobile genetic elements coupled with fitness changes in Drosophila melanogaster.
Concerted transpositions of mobile genetic elements coupled with fitness changes in Drosophila melanogaster.
复制标题
移动遗传元件的协调转位与果蝇适应性变化相结合。
DOI:
10.1093/oxfordjournals.molbev.a040398
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发表时间:
1986
影响因子:
10.7
通讯作者:
V. Gvozdev
中科院分区:
文献类型:
--
作者:
E. Pasyukova;E. Belyaeva;G. Kogan;L. Kaidanov;V. Gvozdev
In an inbred low-activity (LA) strain of Drosophila melanogaster with a low level of fitness and a complex of inadaptive characters, in situ hybridization reveals an invariant pattern of distribution of three copia-like elements (mdg-1, mdg-3, and copia). Rare, spontaneous, multiple transpositions of mobile elements in the LA strain were shown to be coupled with a drastic increase of fitness. A changed pattern of various types of mobile elements was also observed on selecting the LA strain for higher fitness. High-fitness strains show transpositions of mobile elements to definite chromosomal sites ("hot spots"). Concerted changes in the location of three different mobile elements were found to be coupled with an increase of fitness. The mdg-1 distribution patterns were also examined in two low-fitness strains independently selected from the high-fitness ones. Fitness decrease was accompanied by mdg-1 excision from the hot spots of their location usually detected in the high-fitness strains. The results suggest the existence of a system of adaptive transpositions of mobile elements that takes part in fitness control.
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影响因子:
14.9
作者:
Sun,L;Paulson,KE;Schmid,CW;Kadyk,L;Leinwand,L
通讯作者:
Leinwand,L
影响因子:
2.9
作者:
Hall,BG
通讯作者:
Hall,BG
影响因子:
5.6
作者:
DEININGER, PL;JOLLY, DJ;SCHMID, CW
通讯作者:
SCHMID, CW
影响因子:
10.7
作者:
Templeton,AR
通讯作者:
Templeton,AR
DOI:
10.1089/dna.1985.4.1
发表时间:
1985
期刊:
DNA (Mary Ann Liebert, Inc.)
影响因子:
--
作者:
Maurer,RA
通讯作者:
Maurer,RA