Diffuse correlation spectroscopy blood flow monitoring for intraventricular hemorrhage vulnerability in extremely low gestational age newborns.
Diffuse correlation spectroscopy blood flow monitoring for intraventricular hemorrhage vulnerability in extremely low gestational age newborns.
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DOI:
10.1038/s41598-022-16499-3
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发表时间:
2022-07-27
影响因子:
4.6
通讯作者:
El-Dib, Mohamed
中科院分区:
文献类型:
--
作者:
Sunwoo, John;Zavriyev, Alexander, I;Kaya, Kutlu;Martin, Alyssa;Munster, Chelsea;Steele, Tina;Cuddyer, Deborah;Sheldon, Yvonne;Orihuela-Espina, Felipe;Herzberg, Emily M.;Inder, Terrie;Franceschini, Maria Angela;El-Dib, Mohamed
In premature infants with an extremely low gestational age (ELGA, < 29 weeks GA), dysregulated changes in cerebral blood flow (CBF) are among the major pathogenic factors leading to germinal matrix/intraventricular hemorrhage (GM/IVH). Continuous monitoring of CBF can guide interventions to minimize the risk of brain injury, but there are no clinically standard techniques or tools for its measurement. We report the feasibility of the continuous monitoring of CBF, including measures of autoregulation, via diffuse correlation spectroscopy (DCS) in ELGA infants using CBF variability and correlation with scalp blood flow (SBF, served as a surrogate measure of systemic perturbations). In nineteen ELGA infants (with 9 cases of GM/IVH) monitored for 6–24 h between days 2–5 of life, we found a strong correlation between CBF and SBF in severe IVH (Grade III or IV) and IVH diagnosed within 72 h of life, while CBF variability alone was not associated with IVH. The proposed method is potentially useful at the bedside for the prompt assessment of cerebral autoregulation and early identification of infants vulnerable to GM/IVH.
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DOI:
10.1136/bmj.g7635
发表时间:
2015-01-05
期刊:
BMJ (Clinical research ed.)
影响因子:
--
作者:
Hyttel-Sorensen S;Pellicer A;Alderliesten T;Austin T;van Bel F;Benders M;Claris O;Dempsey E;Franz AR;Fumagalli M;Gluud C;Grevstad B;Hagmann C;Lemmers P;van Oeveren W;Pichler G;Plomgaard AM;Riera J;Sanchez L;Winkel P;Wolf M;Greisen G
通讯作者:
Greisen G
DOI:
10.1152/ajpregu.00204.2014
发表时间:
2014-10-01
影响因子:
2.8
作者:
Gagnon, Daniel;Brothers, R. Matthew;Crandall, Craig G.
通讯作者:
Crandall, Craig G.
DOI:
10.1364/josaa.14.000192
发表时间:
1997-01-01
影响因子:
1.9
作者:
Boas, DA;Yodh, AG
通讯作者:
Yodh, AG
影响因子:
3.7
作者:
Haeussinger FB;Heinzel S;Hahn T;Schecklmann M;Ehlis AC;Fallgatter AJ
通讯作者:
Fallgatter AJ
影响因子:
8
作者:
O'Leary H;Gregas MC;Limperopoulos C;Zaretskaya I;Bassan H;Soul JS;Di Salvo DN;du Plessis AJ
通讯作者:
du Plessis AJ