Considering the inclusion of metabolic and cardiovascular markers in the Panel Study of Income Dynamics.
Considering the inclusion of metabolic and cardiovascular markers in the Panel Study of Income Dynamics.
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DOI：
10.1080/19485560903382437
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发表时间：
2009
影响因子：
1.3
通讯作者：
Dowd JB
中科院分区：
文献类型：
--
作者：
Goldman N;Dowd JB
将生物标记物纳入社会调查，如PSID，有可能回答社会科学和公共卫生中的许多难以捉摸的问题，包括被广泛研究的社会经济地位与健康之间的关系。本文综述了PSID中可能包含的心血管和代谢风险的生物标记物。我们首先讨论了将这些生物标记物添加到PSID的可观的分析好处，包括探索生命过程假说和测试社会环境和生物系统之间的因果关系的可能性。接下来，我们回顾了关于心血管和代谢危险因素自我报告的可靠性的证据，结论是依赖自我报告的潜在偏差可能是巨大的。基于生物学重要性的证据以及易于在家中收集的实际考虑，我们推荐的第一级生物标记物包括测量的身高、体重、腰围和臀围、舒张压和收缩压、静息心率、总胆固醇和高密度脂蛋白、糖化血红蛋白(HbA1c)、C反应蛋白(CRP)和胱抑素C。
The inclusion of biomarkers in social surveys such as the PSID has the potential to answer many elusive questions in social science and public health, including the much-studied relationship between socioeconomic status and health. This paper reviews the potential inclusion of biomarkers of cardiovascular and metabolic risk in the PSID. We first discuss the considerable analytical benefits of adding these biomarkers to the PSID, including the exploration of life course hypotheses and the potential to test causal relationships between the social environment and biological systems. Next, we review evidence on the reliability of self-reports of cardiovascular and metabolic risk factors, concluding that the potential bias from relying on self-reports may be substantial. Based on evidence of biological importance as well as practical considerations of ease of in-home collection, our first tier of recommended biomarkers includes measured height, weight, waist and hip circumference, diastolic and systolic blood pressure, resting heart rate, total and HDL cholesterol, glycosylated hemoglobin (HbA1c), C-reactive protein (CRP), and cystatin C. Additional markers of secondary priority are also discussed.
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作者：
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通讯作者：
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