Visual emotional information processing in male schizophrenia patients: Combining ERP, clinical and behavioral evidence
Visual emotional information processing in male schizophrenia patients: Combining ERP, clinical and behavioral evidence
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男性精神分裂症患者的视觉情绪信息处理：结合 ERP、临床和行为证据
DOI：
10.1016/j.neulet.2013.06.022
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发表时间：
2013-08
影响因子：
2.5
通讯作者：
Niznikiewicz, Margaret A.
中科院分区：
文献类型：
--
作者：
Nestor, Paul G.;McCarley, Robert W.;Goncalves, Oscar F.;Niznikiewicz, Margaret A.
我们使用事件相关电位（ERPs）来研究精神分裂症患者视觉情绪加工的时间过程。在19名慢性男性精神分裂症患者和16名健康对照（HC）中，当他们观看用于诱导积极、消极或中性情绪的IAPS图片时，记录了erp，这些图片在三个不同的场合以封锁设计呈现。电生理上，各组在早期电位（观看图像的前200 ms）： C1、P1和N1；在患者组中也发现了较少阳性的、广泛分布的P2。P2振幅仅与患者自我报告的负性情绪相关。两组在晚期电位，特别是晚期正电位（500-1000 ms潜伏期窗口）上没有差异。三种情绪诱导前后患者的负性情绪均较多；然而，情绪诱导对两组人的影响方向相同。两组对唤起性刺激表现出相似的主观效价和唤醒等级。ERP结果表明，在前200 ms内，视觉唤起刺激的加工存在差异，并且精神分裂症患者的视觉唤起刺激加工的早期阶段是异常的，与刺激的效价无关。负面图像处理的感觉异常与负面情绪的相关性表明，患者的感觉异常与负面情绪体验的增加有关。
We used event-related potentials (ERPs) to examine the time course of visual emotion processing in schizophrenia. ERPs were recorded in 19 chronic male schizophrenia patients and 16 healthy controls (HC) while they viewed IAPS pictures used to induce positive, negative, or neutral mood, presented in a blocked design across three separate occasions. Electrophysiologically, groups differences were found in early potentials (the first 200 ms of picture viewing): C1, P1, and N1; also, less positive, broadly distributed P2 was found in the patient group. P2 amplitude to negative valenced pictures only was correlated with self-reported negative mood in the patients. The groups did not differ in late-occurring potentials, specifically the late positive potential (500–1000 ms latency window). Patients reported more negative affect before and after the three types of mood induction; however, mood induction influenced both groups in the same direction. Both groups showed similar subjective valence and arousal ratings of evocative stimuli. The ERP results suggest that visual evocative stimuli are differentially processed within the first 200 ms, and that the early stages of visual evocative stimuli processing are abnormal in schizophrenia, irrespective of stimulus valence. The correlation found between sensory abnormalities in negative pictures processing and negative mood suggests a relationship between abnormal sensory processes and increased negative mood experience in patients.
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影响因子：
10.6
作者：
Dowd, Erin C.;Barch, Deanna M.
通讯作者：
Barch, Deanna M.
影响因子：
6.9
作者：
Pinheiro, A. P.;del Re, E.;Niznikiewicz, M. A.
通讯作者：
Niznikiewicz, M. A.
DOI：
--
发表时间：
1995
期刊：
--
影响因子：
--
作者：
N. Andreasen
通讯作者：
N. Andreasen
影响因子：
4.6
作者：
Horan, William P.;Wynn, Jonathan K.;Kring, Ann M.;Simons, Robert F.;Green, Michael F.
通讯作者：
Green, Michael F.
影响因子：
4.5
作者：
Horan, William P.;Foti, Dan;Hajcak, Greg;Wynn, Jonathan K.;Green, Michael F.
通讯作者：
Green, Michael F.