An optimized transversely isotropic, hyper-poro-viscoelastic finite element model of the meniscus to evaluate mechanical degradation following traumatic loading.

An optimized transversely isotropic, hyper-poro-viscoelastic finite element model of the meniscus to evaluate mechanical degradation following traumatic loading.
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DOI:
10.1016/j.jbiomech.2015.02.028
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发表时间:
2015-06-01
影响因子:
2.4
通讯作者:
Donahue, Tammy L. Haut
Donahue, Tammy L. Haut
中科院分区:
工程技术3区
文献类型:
--
作者:
Wheatley, Benjamin B.;Fischenich, Kristine M.;Button, Keith D.;Haut, Roger C.;Donahue, Tammy L. Haut

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有限元逆分析是预测材料行为、评估力学性能和研究生物组织功能差异的有效方法。半月板在膝关节内的负荷分布中起着关键作用,半月板退化通常与骨关节炎的发作相关。在目前的研究中,一种新的横向各向同性超多孔粘弹性本构方程被纳入到有限元模型中,以评估胫股关节撞击后关节材料特性的变化。一个非线性优化方案被用来拟合模型输出压痕松弛实验数据。这项研究是第一个调查的放松率在健康与影响的椎间盘。在撞击后12周,发现刚度降低(p=0.003),而组织松弛率增加(p=0.010)。然而,受影响组织的松弛总量没有变化(p=0.513)。
Inverse finite element (FE) analysis is an effective method to predict material behavior, evaluate mechanical properties, and study differences in biological tissue function. The meniscus plays a key role in load distribution within the knee joint and meniscal degradation is commonly associated with the onset of osteoarthritis. In the current study, a novel transversely isotropic hyper-poro-viscoelastic constitutive formulation was incorporated in a FE model to evaluate changes in meniscal material properties following tibiofemoral joint impact. A non-linear optimization scheme was used to fit the model output to indentation relaxation experimental data. This study is the first to investigate rate of relaxation in healthy versus impacted menisci. Stiffness was found to be decreased (p=0.003), while the rate of tissue relaxation increased (p=0.010) at twelve weeks post impact. Total amount of relaxation, however, did not change in the impacted tissue (p=0.513).
DOI: 10.1115/1.4027468
发表时间: 2014-07-01
影响因子: 1.7
作者:
Fischenich, Kristine M.;Coatney, Garrett A.;Donahue, Tammy L. Haut
通讯作者: Donahue, Tammy L. Haut
DOI: 10.1016/j.jbiomech.2014.11.038
发表时间: 2015-01-21
影响因子: 2.4
作者:
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