Variations of telencephalic development that paved the way for neocortical evolution.
Variations of telencephalic development that paved the way for neocortical evolution.
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DOI：
10.1016/j.pneurobio.2020.101865
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发表时间：
2020-11
影响因子：
6.7
通讯作者：
Molnár Z
中科院分区：
文献类型：
--
作者：
García-Moreno F;Molnár Z
为了揭示大脑皮层是如何在进化过程中出现的，我们需要了解大脑皮层发育的进化过程。皮质细胞的发育轨迹是理解进化变化和同源性的基础。早期大脑发育的细微变化解释了脊椎动物苍白球和新皮质起源的多样性。查尔斯·达尔文曾说过：“胚胎结构中的群落揭示了世系共同体”。因此，为了了解新大脑皮层是如何在哺乳动物进化过程中出现的，我们需要了解大脑皮层的发育进化，大脑皮层是新大脑皮层的来源。在这篇文章中，我们回顾了大脑皮层发育的变化，使六层新皮质的产生成为可能。我们认为，大脑发育早期的微妙变化的积累，解释了脊椎动物苍白球的多样化和新皮质的起源。最初，可分泌的形态原表达的微弱差异促进了不同脊椎动物早期大脑皮层部分的比例和组织的广泛差异。它促使不同的部门接纳不同的祖先和不同的萌发区。这些细胞和萌发室产生不同的神经元种群，它们以分类单元特有的方式通过径向和切向迁移相互迁移和混合。总而言之，这些早期的变异对神经遗传梯度、分层、定位和连通性产生了深远的影响。大脑皮质神经元的基因表达、生物学和生理特性是推测同源性的重要特征，但细胞的起源及其发育轨迹是理解进化变化的基础。我们的综述比较了蜥蜴类和哺乳动物的同源皮质部分的发育，特别关注细胞谱系，以寻找导致哺乳动物新皮质出现的关键变化。
To reveal how the neocortex emerged during evolution we need to understand the evolution of the development of the pallium. The developmental trajectories of cortical cells are fundamental to understand evolutionary changes and homologies. Subtle variations from early brain development accounted for the diversification of vertebrate pallia and neocortical origin. Charles Darwin stated, “community in embryonic structure reveals community of descent”. Thus, to understand how the neocortex emerged during mammalian evolution we need to understand the evolution of the development of the pallium, the source of the neocortex. In this article, we review the variations in the development of the pallium that enabled the production of the six-layered neocortex. We propose that an accumulation of subtle modifications from very early brain development accounted for the diversification of vertebrate pallia and the origin of the neocortex. Initially, faint differences of expression of secretable morphogens promote a wide variety in the proportions and organization of sectors of the early pallium in different vertebrates. It prompted different sectors to host varied progenitors and distinct germinative zones. These cells and germinative compartments generate diverse neuronal populations that migrate and mix with each other through radial and tangential migrations in a taxon-specific fashion. Together, these early variations had a profound influence on neurogenetic gradients, lamination, positioning, and connectivity. Gene expression, hodology, and physiological properties of pallial neurons are important features to suggest homologies, but the origin of cells and their developmental trajectory are fundamental to understand evolutionary changes. Our review compares the development of the homologous pallial sectors in sauropsids and mammals, with a particular focus on cell lineage, in search of the key changes that led to the appearance of the mammalian neocortex.
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影响因子：
10.5
作者：
Arnold, Sebastian J.;Huang, Guo-Jen;Groszer, Matthias
通讯作者：
Groszer, Matthias
影响因子：
2.5
作者：
ALTMAN, J;BAYER, SA
通讯作者：
BAYER, SA
影响因子：
4.6
作者：
Caronia-Brown, Giuliana;Yoshida, Michio;Grove, Elizabeth A.
通讯作者：
Grove, Elizabeth A.
影响因子：
4.3
作者：
Bosman CA;Aboitiz F
通讯作者：
Aboitiz F
影响因子：
9.2
作者：
Briscoe, Steven D.;Albertin, Caroline B.;Ragsdale, Clifton W.
通讯作者：
Ragsdale, Clifton W.