Pediatric Magnetoencephalography in Clinical Practice and Research.
Pediatric Magnetoencephalography in Clinical Practice and Research.
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DOI：
10.1016/j.nic.2020.02.002
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发表时间：
2020-05
影响因子：
2.3
通讯作者：
Chen YH
中科院分区：
文献类型：
--
作者：
Papadelis C;Chen YH
脑磁图（MEG）是一种非侵入性的神经成像技术，它测量人脑产生的电磁场。这些场的主要来源被认为是皮层锥体细胞的顶端树突中的突触后电流，1尽管也可以记录动作电位。2，3脑磁图提供了亚毫秒范围内的出色时间分辨率，甚至可以记录高频率的大脑活动。4 MEG还通过磁源成像（MSI）提供良好的空间分辨率。5，6它对与头皮表面相切的电流最敏感，而对径向源产生的磁场视而不见。7，8在临床实践中，MEG主要用于手术治疗耐药癫痫患者的致痫灶定位。9，10 MEG也已成为了解成人和儿童大脑的流行。11在MEG记录期间，患者或受试者舒适地坐在位于磁屏蔽室内的扶手椅上，该房间专门设计用于防止环境的电磁噪声压倒弱神经电磁场。在几种情况下，同时进行高密度脑电图（EEG）记录（图1）。当患者处于镇静状态或需要睡眠时，也可以在仰卧位进行记录。磁屏蔽室配备了可调节的照明和视听通信系统，可以进行通信
Magnetoencephalography (MEG) is a noninvasive neuroimaging technique that measures the electromagnetic fields generated by the human brain. The main sources of these fields are considered to be the postsynaptic currents in the apical dendrites of the cortical pyramidal cells, 1 although action potentials also may be recorded. 2, 3 MEG offers an excellent temporal resolution in the range of submilliseconds, that allows even brain activity with high frequencies to be recorded. 4 MEG also offers good spatial resolution via magnetic source imaging (MSI). 5, 6 It is most sensitive to the currents that are tangential to the surface of the scalp and blind to magnetic fields produced by radial sources. 7, 8In clinical practice, MEG is used mostly for the localization of epileptogenic foci in patients with drug-resistant epilepsy undergoing surgery. 9, 10 MEG also has become popular for understanding the human brain in both adults and children. 11 During an MEG recording, the patient or subject sits comfortably in an armchair that is located inside a magnetically shielded room, which is specially designed to prevent the electromagnetic noise of the environment from overwhelming the weak neural electromagnetic fields. In several occasions, simultaneous high-density electroencephalogram (EEG) recordings are performed (Fig. 1). Recording also can be performed in a supine position when a patient is under sedation or needs to sleep. The magnetically shielded room is equipped with adjustable lighting and an audiovisual communication system that allows communication
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影响因子：
2.9
作者：
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影响因子：
2.9
作者：
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通讯作者：
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