SARS-CoV-2 Infection and Oral Health: Therapeutic Opportunities and Challenges.
SARS-CoV-2 Infection and Oral Health: Therapeutic Opportunities and Challenges.
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DOI：
10.3390/jcm10010156
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发表时间：
2021-01-05
影响因子：
3.9
通讯作者：
Gangula PR
中科院分区：
文献类型：
--
作者：
Coke CJ;Davison B;Fields N;Fletcher J;Rollings J;Roberson L;Challagundla KB;Sampath C;Cade J;Farmer-Dixon C;Gangula PR
新型冠状病毒--严重急性呼吸综合征冠状病毒-2(SARS-CoV-2)及其引起的疾病--新冠肺炎(CoronaVirus Disease-2019年)直接和间接地在全球范围内对许多生命产生了多方面的影响。越来越多的证据表明，新冠肺炎患者会经历几种口腔健康问题，如口干、粘膜起泡、口疹、嘴唇坏死以及味觉和嗅觉丧失。牙周病(PD)是一种严重的牙周炎，可能会加剧与新冠肺炎相关的症状。常规的牙科和牙周治疗可能有助于减轻新冠肺炎的症状。帕金森病在患有肥胖、糖尿病和心血管风险等代谢性疾病的患者中更为常见。研究表明，这些患者对SARS-CoV-2感染高度易感。已知导致帕金森病和其他代谢性疾病发展的促炎细胞因子和氧化应激在新冠肺炎患者中高度升高。牙周健康状况可能有助于确定新冠肺炎感染的严重程度。越来越多的证据表明，与美国其他种族相比，非洲裔美国人(AA)和弱势群体更容易患帕金森病、代谢性疾病和新冠肺炎。牙科和牙科保健专业人员特别容易感染这种病毒，因为这种病毒可以通过口腔传播，并使用在该领域普遍存在的气雾剂制造工具。在这篇综述中，我们试图提供一个全面和最新的关于SARS-CoV-2/新冠肺炎的信息来源，以及它对牙科专业和患者去牙科诊所就诊的各种影响。最后，这篇综述对于口腔卫生的管理和降低感染的严重程度是一个有价值的资源。
The novel corona virus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), and the disease it causes, COVID-19 (Coronavirus Disease-2019) have had multi-faceted effects on a number of lives on a global scale both directly and indirectly. A growing body of evidence suggest that COVID-19 patients experience several oral health problems such as dry mouth, mucosal blistering, mouth rash, lip necrosis, and loss of taste and smell. Periodontal disease (PD), a severe inflammatory gum disease, may worsen the symptoms associated with COVID-19. Routine dental and periodontal treatment may help decrease the symptoms of COVID-19. PD is more prevalent among patients experiencing metabolic diseases such as obesity, diabetes mellitus and cardiovascular risk. Studies have shown that these patients are highly susceptible for SARS-CoV-2 infection. Pro-inflammatory cytokines and oxidative stress known to contribute to the development of PD and other metabolic diseases are highly elevated among COVID-19 patients. Periodontal health may help to determine the severity of COVID-19 infection. Accumulating evidence shows that African-Americans (AAs) and vulnerable populations are disproportionately susceptible to PD, metabolic diseases and COVID-19 compared to other ethnicities in the United States. Dentistry and dental healthcare professionals are particularly susceptible to this virus due to the transferability via the oral cavity and the use of aerosol creating instruments that are ubiquitous in this field. In this review, we attempt to provide a comprehensive and updated source of information about SARS-CoV-2/COVID-19 and the various effects it has had on the dental profession and patients visits to dental clinics. Finally, this review is a valuable resource for the management of oral hygiene and reduction of the severity of infection.
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影响因子：
0.8
作者：
Daniel R;Gokulanathan S;Shanmugasundaram N;Lakshmigandhan M;Kavin T
通讯作者：
Kavin T
DOI：
10.1016/j.eurox.2019.100021
发表时间：
2019-07-01
影响因子：
2.6
作者：
Arias-Herrera, Santiago;Bascones-Ilundian, Cristina;Bascones-Martinez, Antonio
通讯作者：
Bascones-Martinez, Antonio
DOI：
10.1111/jopr.13220
发表时间：
2020-07-24
影响因子：
4
作者：
Bidra, Avinash S.;Pelletier, Jesse S.;Tessema, Belachew
通讯作者：
Tessema, Belachew
影响因子：
5.5
作者：
Botros, Nathalie;Iyer, Parvati;Ojcius, David M.
通讯作者：
Ojcius, David M.
DOI：
10.3390/ijerph17093151
发表时间：
2020-05-01
影响因子：
--
作者：
Dar-Odeh, Najla;Babkair, Hamzah;Abu-Hammad, Osama
通讯作者：
Abu-Hammad, Osama