Effects of Exercise on the Structure and Circulation of Choroid in Normal Eyes.
Effects of Exercise on the Structure and Circulation of Choroid in Normal Eyes.
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DOI：
10.1371/journal.pone.0168336
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Mitamura Y
中科院分区：
文献类型：
--
作者：
Kinoshita T;Mori J;Okuda N;Imaizumi H;Iwasaki M;Shimizu M;Miyamoto H;Akaiwa K;Semba K;Sonoda S;Sakamoto T;Mitamura Y
目的：探讨动态运动对正常眼脉络膜循环、脉络膜腔面积和基质面积的影响。这是一项前瞻性的干预性研究，38例正常人的38只眼，通过邀请。记录轻度动态运动前和运动后即刻的收缩压、舒张压、心率、眼压、平均眼灌注压（MOPP）、脉络膜血流速度和增强深度成像光学相干断层扫描（EDI-OCT）图像。休息10分钟后记录相同的测量结果。用激光散斑血流图测量脉络膜血流速度，以平均模糊率作为评价指标。将中心凹下脉络膜的水平EDI-OCT图像转换为二值图像。从这些图像中确定中心脉络膜厚度（CCT）、脉络膜总横截面面积、管腔面积、基质面积以及管腔面积与脉络膜总面积的比率（L/C比率）。收缩压、舒张压、心率、MOPP和平均模糊率在运动后即刻显著升高，在运动后10分钟显著降低。运动后平均CCT、平均脉络膜总面积、平均脉络膜腔和基质面积以及平均L/C比值均无显著变化。我们的研究结果表明，在测量血流速度之前需要休息一段时间，但EDI-OCT成像确定脉络膜厚度和面积并不必要。
To determine the effects of dynamic exercise on the circulation and the luminal and stromal areas of the choroid in normal eyes. This was a prospective interventional study of 38 eyes of 38 normal subjects enrolled by invitation. The systolic and diastolic blood pressures, heart rate, intraocularpressure, mean ocular perfusion pressure (MOPP), choroidal blood velocity, and enhanced depth imaging optical coherence tomographic (EDI-OCT) images were recorded before, and immediately after mild dynamic exercise. The same measurements were recorded after 10 min of rest. The choroidal blood velocity was measured bylaser speckle flowgraphy, and the mean blur rate was used for the evaluations. The horizontal EDI-OCT images of the subfoveal choroid were converted to binary images. The central choroidal thickness (CCT), total cross sectional choroidal area, luminal areas, stromal areas, and the ratio of luminal area to total choroidal area (L/C ratio) were determined from these images. The systolic and diastolic blood pressures, heart rate, MOPP, and the mean blur rate were significantly increased immediately after the exercise and significantly decreased 10 minutes after the exercise. There wereno significant changes in the mean CCT, the mean total choroidal area, the mean luminal and stromal areas, and the mean L/C ratio after the exercise. Our results suggest that a rest period is needed before measurements of blood flow velocity but not necessary for the EDI-OCT imaging to determine the choroidal thickness and area.
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DOI：
10.1007/s00417-002-0552-1
发表时间：
2002-10-01
影响因子：
2.7
作者：
Németh, J;Knézy, K;Harkányi, Z
通讯作者：
Harkányi, Z
影响因子：
2
作者：
Iwata A;Mitamura Y;Niki M;Semba K;Egawa M;Katome T;Sonoda S;Sakamoto T
通讯作者：
Sakamoto T
影响因子：
17.8
作者：
Kur, Joanna;Newman, Eric A.;Chan-Ling, Tailoi
通讯作者：
Chan-Ling, Tailoi
影响因子：
4.4
作者：
Fuchsjäger-Mayrl, G;Luksch, A;Schmetterer, L
通讯作者：
Schmetterer, L
影响因子：
3.9
作者：
BILL, A;SPERBER, GO
通讯作者：
SPERBER, GO