Binarization of enhanced depth imaging optical coherence tomographic images of an eye with Wyburn-Mason syndrome: a case report.
Binarization of enhanced depth imaging optical coherence tomographic images of an eye with Wyburn-Mason syndrome: a case report.
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DOI：
10.1186/s12886-015-0014-2
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发表时间：
2015-03-07
影响因子：
2
通讯作者：
Sakamoto T
中科院分区：
文献类型：
--
作者：
Iwata A;Mitamura Y;Niki M;Semba K;Egawa M;Katome T;Sonoda S;Sakamoto T
报告一例Wyburn-Mason综合征眼的脉络膜增厚和脉络膜腔面积增大。据我们所知，这是第一个报告表明脉络膜厚度和腔面积增加的情况下，Wyburn-Mason综合征。此外，我们报告了16年来视网膜动静脉畸形的外观变化。一位27岁的女性，在11岁时被诊断出患有Wyburn-Mason综合征，来到我们的诊所。她的右眼最佳矫正视力为20/12.5，左眼有光感。严重扩张、迂曲的血管环从视盘分布到左眼底的所有四个象限。某些区域的血管环比16年前更加扩张和扭曲。光学相干断层扫描（OCT）显示左眼视网膜水肿伴囊性变化和脉络膜血管腔扩大。在增强深度成像OCT（EDI-OCT）图像中，通过卡尺功能手动测量中心凹下脉络膜厚度。EDI-OCT图像的二值化使用可公开访问的ImageJ软件进行。中心凹下脉络膜的检查区域为1，500 μm宽，通过Niblack方法追踪代表管腔区域的暗区。在确定每个像素的距离后，自动计算管腔面积。右眼中心凹下脉络膜厚度为250 μm，左眼为462 μm。右眼和左眼中1，500 μ m宽的中心凹下脉络膜的管腔面积分别为307，165.6 μm2和545，780.7 μm2。EDI-OCT图像显示脉络膜较厚，EDI-OCT图像的二值化显示受累眼的管腔面积明显较大，表明脉络膜血管扩张。结果表明，EDI-OCT图像转换为二值图像是一种有用的方法来量化脉络膜结构。
To report a thicker choroid and larger choroidal luminal area in an eye with Wyburn-Mason syndrome. To the best of our knowledge, this is the first report demonstrating an increase in the choroidal thickness and the luminal area in a case of Wyburn-Mason syndrome. In addition, we report the changing appearance of retinal arteriovenous malformations over a 16-year period. A 27-year-old woman, who was diagnosed with Wyburn-Mason syndrome at age 11 years, visited our clinic. Her best-corrected visual acuity was 20/12.5 in the right eye and light perception in the left eye. Severely dilated, tortuous vascular loops were distributed from the optic disc over all four quadrants of the left fundus. The vascular loops in some areas were more dilated and tortuous than 16 years earlier. Optical coherence tomography (OCT) showed retinal edema with cystic changes and enlarged choroidal vessel lumens in the left eye. The subfoveal choroidal thickness was manually measured by the caliper function in the enhanced depth imaging OCT (EDI-OCT) images. Binarization of the EDI-OCT images was performed with publicly accessible ImageJ software. The examined area of the subfoveal choroid was 1,500 μm wide, and the dark areas representing the luminal areas were traced by the Niblack method. After determining the distance of each pixel, the luminal area was automatically calculated. The subfoveal choroidal thickness was 250 μm in the right eye and 462 μm in the left eye. The luminal area of the 1,500-μm-wide subfoveal choroid was computed to be 307,165.6 μm2 in the right eye and 545,780.7 μm2 in the left eye. The EDI-OCT images showed a thicker choroid, and binarization of the EDI-OCT images showed that the luminal areas were significantly larger in the affected eye, suggesting a dilatation of the choroidal vessels. The results demonstrated that conversion of EDI-OCT images to binary images was a useful method to quantify the choroidal structure.
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影响因子：
13.7
作者：
Branchini LA;Adhi M;Regatieri CV;Nandakumar N;Liu JJ;Laver N;Fujimoto JG;Duker JS
通讯作者：
Duker JS
影响因子：
3.7
作者：
Sohrab M;Wu K;Fawzi AA
通讯作者：
Fawzi AA
影响因子：
8.1
作者：
Fileta, John B;Bennett, Timothy J;Quillen, David A
通讯作者：
Quillen, David A
影响因子：
2
作者：
Qin, Xue-jiao;Huang, Chao;Lai, Kun
通讯作者：
Lai, Kun
影响因子：
2.9
作者：
Reck, SD;Zacks, DN;Eibschitz-Tsimhoni, M
通讯作者：
Eibschitz-Tsimhoni, M