The Ontology Lookup Service, a lightweight cross-platform tool for controlled vocabulary queries.

The Ontology Lookup Service, a lightweight cross-platform tool for controlled vocabulary queries.
复制标题

DOI:
10.1186/1471-2105-7-97
复制
发表时间:
2006-02-28
期刊:
影响因子:
3
通讯作者:
Hermjakob H
Hermjakob H
中科院分区:
生物学4区
文献类型:
--
作者:
Côté RG;Jones P;Apweiler R;Hermjakob H

文献摘要

参考文献

被引文献

相似文献

随着高通量分析方法生成大量的生物医学数据,受控的词汇和本体学对注释信息单位越来越重要,以方便搜索和检索。每个科学界都倾向于创建自己的本地本体论。查询这些本体论的界面往往因组而异。我们看到需要一个集中位置来执行受控词汇查询,该查询将提供轻巧的Web访问用户界面以及一致的自动查询统一肥皂界面。 创建了本体查找服务(OLS)是为了将公开可用的生物医学本体论整合到一个数据库中。所有修改的本体论每天都会更新。当前已加载的本体论的列表可在线提供。可以查询数据库以获取有关单个项的信息或使用AJAX浏览完整的本体。自动完成提供了一种用户友好的搜索机制。可以使用基于AJAX的本体查看器来浏览完整的本体或子集。可以使用SOAP查询Web服务的程序化接口。该服务由WSDL描述符文件描述。使用SOAP可以从SourceForge下载示例Java客户端以使用SOAP连接到Web服务。所有OLS源代码均在开源Apache许可证下公开可用。 OLS为开放的生物医学本体(OBO)格式提供了一个用户友好的单个入口点。可以在交互式或编程上访问它。
With the vast amounts of biomedical data being generated by high-throughput analysis methods, controlled vocabularies and ontologies are becoming increasingly important to annotate units of information for ease of search and retrieval. Each scientific community tends to create its own locally available ontology. The interfaces to query these ontologies tend to vary from group to group. We saw the need for a centralized location to perform controlled vocabulary queries that would offer both a lightweight web-accessible user interface as well as a consistent, unified SOAP interface for automated queries. The Ontology Lookup Service (OLS) was created to integrate publicly available biomedical ontologies into a single database. All modified ontologies are updated daily. A list of currently loaded ontologies is available online. The database can be queried to obtain information on a single term or to browse a complete ontology using AJAX. Auto-completion provides a user-friendly search mechanism. An AJAX-based ontology viewer is available to browse a complete ontology or subsets of it. A programmatic interface is available to query the webservice using SOAP. The service is described by a WSDL descriptor file available online. A sample Java client to connect to the webservice using SOAP is available for download from SourceForge. All OLS source code is publicly available under the open source Apache Licence. The OLS provides a user-friendly single entry point for publicly available ontologies in the Open Biomedical Ontology (OBO) format. It can be accessed interactively or programmatically at .
DOI: 10.1101/gr.403602
发表时间: 2002-10-01
期刊: GENOME RESEARCH
影响因子: 7
作者:
Stein, LD;Mungall, C;Lewis, S
通讯作者: Lewis, S
DOI: 10.1093/nar/gkg516
发表时间: 2003-07-01
影响因子: 14.9
作者:
Phan, IQH;Pilbout, SF;Bairoch, A
通讯作者: Bairoch, A
DOI: 10.1186/1471-2105-2-7
发表时间: 2001
期刊: BMC bioinformatics
影响因子: 3
作者:
Dowell RD;Jokerst RM;Day A;Eddy SR;Stein L
通讯作者: Stein L
DOI: 10.1093/nar/gkh052
发表时间: 2004-01-01
影响因子: 14.9
作者:
Hermjakob, H;Montecchi-Palazzi, L;Apweller, R
通讯作者: Apweller, R
DOI: 10.1002/pmic.200401303
发表时间: 2005-08-01
期刊: PROTEOMICS
影响因子: 3.4
作者:
Martens, L;Hermjakob, H;Apweiler, R
通讯作者: Apweiler, R