Bioaccessibility of metals in alloys: evaluation of three surrogate biofluids.
Bioaccessibility of metals in alloys: evaluation of three surrogate biofluids.
复制标题
合金中金属的生物可及性:三种替代生物流体的评估。
DOI:
10.1016/j.envpol.2013.10.006
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发表时间:
2014
期刊:
影响因子:
--
通讯作者:
Anderson,KimA
中科院分区:
文献类型:
--
作者:
Hillwalker,WendyE;Anderson,KimA
Bioaccessibilityin vitrotests measure the solubility of materials in surrogate biofluids. However, the lack of uniform methods and the effects of variable test parameters on material solubility limit interpretation. One aim of this study was to measure and compare bioaccessibility of selected economically important alloys and metals in surrogate physiologically based biofluids representing oral, inhalation and dermal exposures. A second aim was to experimentally test different biofluid formulations and residence timesin vitro. A third aim was evaluation of dissolution behavior of alloys within vitrolung and dermal biofluid surrogates. This study evaluated the bioaccessibility of sixteen elements in six alloys and 3 elemental/metal powders. We found that the alloys/metals, the chemical properties of the surrogate fluid, and residence time all had major impacts on metal solubility. The large variability of bioaccessibility indicates the relevancy of assessing alloys as toxicologically distinct relative to individual metals.
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影响因子:
3.4
作者:
Henderson, Rayetta G.;Cappellini, Danielle;Oiler, Adriana R.
通讯作者:
Oiler, Adriana R.
DOI:
10.1039/b307520f
发表时间:
2003
期刊:
Journal of environmental monitoring : JEM
影响因子:
--
作者:
Tom Brock;W. Stopford
通讯作者:
W. Stopford
影响因子:
4.8
作者:
J. Skeaff;D. J. Hardy;P. King
通讯作者:
P. King
影响因子:
8.3
作者:
Herting, G.;Wallinder, I. Odnevall;Leygraf, C.
通讯作者:
Leygraf, C.
影响因子:
10
作者:
Hedberg Y;Gustafsson J;Karlsson HL;Möller L;Odnevall Wallinder I
通讯作者:
Odnevall Wallinder I